Publication Name	World Journal of Clinical Cases
Manuscript ID	95363
Country	China

Received	2024-04-30 14:50
Peer-Review Started	2024-04-30 14:50
To Make the First Decision
Return for Revision	2024-05-21 13:15
Revised	2024-06-06 15:08
Second Decision	2024-06-19 02:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-06-19 08:42
Articles in Press	2024-06-19 08:42
Publication Fee Transferred	2024-06-24 14:06
Edit the Manuscript by Language Editor	2024-07-02 05:22
Typeset the Manuscript	2024-07-08 01:31
Publish the Manuscript Online	2024-07-11 09:22

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Correlation between TEX14 and ADAM17 expressions in elderly colorectal cancer tissues and neoplasm staging, invasion, and metastasis
Manuscript Source	Unsolicited Manuscript
All Author List	Gun Chen, Ling-Hua Cong, Chi-Jiang Gu and Ping Li
ORCID	Author(s) ORCID Number Gun Chen http://orcid.org/0009-0008-4204-8420
Funding Agency and Grant Number
Corresponding Author	Gun Chen, BMed, Associate Chief Physician, Department of Pathology, The Affiliated People's Hospital of Ningbo University, No. 251 Baizhang Street, Yinzhou District, Ningbo 315000, Zhejiang Province, China. nbmike0139@163.com
Key Words	The elderly; Colorectal cancer; TEX14; ADAM17; Staging; Invasion; Metastasis
Core Tip	This research retrospectively harvested clinical data from 86 elderly patients pathologically diagnosed with colorectal cancer, seeking to explore the impact of testis expressed gene 14 (TEX14) and A disintegrin and metalloprotease 17 (ADAM17) expressions in elderly colorectal cancer (CRC) tissues on tumor staging, invasion, and metastasis. The outcomes uncovered high expressions of TEX14 and ADAM17 in tumor tissues, which were highly correlated with tumor staging, invasion, and metastasis. This suggests that TEX14 and ADAM17 could serve as effective biomarkers for diagnosing and evaluating the progression of CRC in the elderly.
Publish Date	2024-07-11 09:22
Citation	<p>Chen G, Cong LH, Gu CJ, Li P. Correlation between TEX14 and ADAM17 expressions in elderly colorectal cancer tissues and neoplasm staging, invasion, and metastasis. <i>World J Clin Cases</i> 2024; 12(24): 5492-5501</p>
URL	https://www.wjgnet.com/2307-8960/full/v12/i24/5492.htm
DOI	https://dx.doi.org/10.12998/wjcc.v12.i24.5492

Full Article (PDF)	WJCC-12-5492-with-cover.pdf
Manuscript File	95363-Review-Filipodia.docx
Answering Reviewers	95363-answering-reviewers.pdf
Audio Core Tip	95363-audio.m4a
Biostatistics Review Certificate	95363-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	95363-conflict-of-interest-statement.pdf
Copyright License Agreement	95363-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s)	95363-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	95363-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	95363-non-native-speakers.pdf
Peer-review Report	95363-peer-reviews.pdf
Scientific Misconduct Check	95363-scientific-misconduct-check.png
Scientific Editor Work List	95363-scientific-editor-work-list.pdf
CrossCheck Report	95363-crosscheck-report.pdf