Publication Name	World Journal of Gastroenterology
Manuscript ID	95371
Country	China

Received	2024-04-09 01:32
Peer-Review Started	2024-04-09 01:32
To Make the First Decision
Return for Revision	2024-08-10 19:20
Revised	2024-08-23 11:08
Second Decision	2024-09-12 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-09-12 03:19
Articles in Press	2024-09-12 03:19
Publication Fee Transferred	2024-09-15 03:38
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-09-23 02:55
Publish the Manuscript Online	2024-09-26 08:22

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Effects and mechanisms of Helicobacter pylori infection on the occurrence of extra-gastric tumors
Manuscript Source	Unsolicited Manuscript
All Author List	Shi-Qing Zhao, Hui-Ling Zheng, Xiao-Tian Zhong, Zi-Ye Wang, Yi Su and Yan-Yan Shi
ORCID	Author(s) ORCID Number Yan-Yan Shi http://orcid.org/0000-0003-0247-371X
Funding Agency and Grant Number	Funding Agency Grant Number Beijing Natural Science Foundation J230002
Corresponding Author	Yan-Yan Shi, MD, Professor, Research Center of Clinical Epidemiology, Peking University Third Hospital, No. 49 Garden North Road, Haidian District, Beijing 100191, China. shiyanyan@bjmu.edu.cn
Key Words	Helicobacter pylori; Extra-gastric tumors; Immune system response; Mucosal barrier; Gut microbiome
Core Tip	Apart from gastric diseases, several studies have revealed an association between Helicobacter pylori (H. pylori) and extra-gastric diseases, including cancers. Inflammation, systemic immune responses, microbiome disorders, and hypergastrinemia caused by H. pylori may change the tumor microenvironment and eventually contribute to extra-gastric carcinogenesis. However, the research in this field remains controversial. We summarized the effects of H. pylori infection on the occurrence of extra-gastric tumors and their possible mechanisms, hoping to provide insights for clinical treatment and management of H. pylori-related extra-gastric tumors, as well as help improve prognosis.
Publish Date	2024-09-26 08:22
Citation	<p>Zhao SQ, Zheng HL, Zhong XT, Wang ZY, Su Y, Shi YY. Effects and mechanisms of Helicobacter pylori infection on the occurrence of extra-gastric tumors. <i>World J Gastroenterol</i> 2024; 30(37): 4090-4103</p>
URL	https://www.wjgnet.com/1007-9327/full/v30/i37/4090.htm
DOI	https://dx.doi.org/10.3748/wjg.v30.i37.4090

Full Article (PDF)	WJG-30-4090-with-cover.pdf
Manuscript File	95371_Auto_Edited_004925.docx
Answering Reviewers	95371-answering-reviewers.pdf
Audio Core Tip	95371-audio.mp3
Conflict-of-Interest Disclosure Form	95371-conflict-of-interest-statement.pdf
Copyright License Agreement	95371-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	95371-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	95371-non-native-speakers.pdf
Peer-review Report	95371-peer-reviews.pdf
Scientific Misconduct Check	95371-scientific-misconduct-check.png
Scientific Editor Work List	95371-scientific-editor-work-list.pdf
CrossCheck Report	95371-crosscheck-report.png
CrossCheck Report	95371-crosscheck-report.pdf