Publication Name	World Journal of Gastroenterology
Manuscript ID	9544
Country	Italy

Received	2014-02-16 21:11
Peer-Review Started	2014-02-16 21:32
First Decision by Editorial Office Director
Return for Revision	2014-03-31 10:14
Revised	2014-04-18 00:00
Publication Fee Transferred
Second Decision by Editor	2014-05-26 21:30
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2014-05-26 21:48
Articles in Press	2014-05-26 22:05
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-09-12 14:43
Publish the Manuscript Online	2014-10-07 17:32

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Pathology
Manuscript Type	Retrospective Study
Article Title	Revisiting the role of pathological analysis in transarterial chemoembolization-treated hepatocellular carcinoma after transplantation
Manuscript Source	Unsolicited Manuscript
All Author List	Francesco Vasuri, Deborah Malvi, Francesca Rosini, Pamela Baldin, Michelangelo Fiorentino, Alexandro Paccapelo, Giorgio Ercolani, Antonio Daniele Pinna, Rita Golfieri, Antonio Maria Morselli-Labate, Walter Franco Grigioni and Antonia D’Errico-Grigioni
Funding Agency and Grant Number
Corresponding Author	Antonia D’Errico-Grigioni, MD, “F. Addarii” Institute of Oncology and Transplantation Pathology, S.Orsola-Malpighi Hospital, Bologna University, V.le Ercolani 4/2, 40138 Bologna, Italy. derrico@aosp.bo.it
Key Words	Chemoembolization; Hepatocellular carcinoma; Histopathology; Orthotopic liver transplantation; Cancer recurrence; Transarterial chemoembolization
Core Tip	Transarterial chemoembolization (TACE) of hepatocellular carcinoma (HCC) is used for down-staging before orthotopic liver transplantation (OLT), and as “bridging therapy” to reduce the drop-out rates in the waiting list. A discrepancy exists between the pre-transplant (radiological) and post-transplant (pathological) staging. Few study analyzing the histology of TACE-treated HCC exist. Here we analyzed 11 histological variables in 275 nodules from 101 consecutive OLT recipients and we computed a histological score to stratify recipients into 3 risk groups, with 3.3%, 18.5% and 53.8% respectively of tumor recurrence rates. The histological score allows a better stratification of those recipients beyond the Milan criteria after OLT.
Publish Date	2014-10-07 17:32
Citation	Vasuri F, Malvi D, Rosini F, Baldin P, Fiorentino M, Paccapelo A, Ercolani G, Pinna AD, Golfieri R, Morselli-Labate AM, Grigioni WF, D’Errico-Grigioni A. Revisiting the role of pathological analysis in transarterial chemoembolization-treated hepatocellular carcinoma after transplantation. World J Gastroenterol 2014; 20(37): 13538-13545
URL	http://www.wjgnet.com/1007-9327/full/v20/i37/13538.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i37.13538

Full Article (PDF)	WJG-20-13538.pdf
Full Article (Word)	WJG-20-13538.doc
Manuscript File	9544-Review.doc
Answering Reviewers	9544-Answering reviewers.pdf
Copyright License Agreement	9544-Copyright agreement.pdf
Peer-review Report	9544-Peer review.pdf
Scientific Misconduct Check	9544-CrossCheck.jpg
Scientific Editor Work List	9544-Scientific editor work list.pdf