Publication Name	World Journal of Clinical Cases
Manuscript ID	95491
Country	China

Received	2024-04-11 08:39
Peer-Review Started	2024-04-11 08:39
To Make the First Decision
Return for Revision	2024-05-09 23:37
Revised	2024-05-28 07:10
Second Decision	2024-06-17 02:47
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-06-17 09:05
Articles in Press	2024-06-17 09:05
Publication Fee Transferred	2024-06-22 02:47
Edit the Manuscript by Language Editor	2024-06-30 20:59
Typeset the Manuscript	2024-07-01 09:11
Publish the Manuscript Online	2024-07-05 10:19

ISSN	2307-8960 (online)
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Category	Genetics & Heredity
Manuscript Type	Case Report
Article Title	Fatal multiple acyl-CoA dehydrogenase deficiency caused by ETFDH gene mutation: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Xue-Xia Li, Xiao-Nan Yang, Hu-Dan Pan and Liang Liu
ORCID	Author(s) ORCID Number Xue-Xia Li http://orcid.org/0000-0001-9827-5093
Funding Agency and Grant Number
Corresponding Author	Xue-Xia Li, MD, Doctor, Doctor, Department of Nephrology, Zhuhai Hospital of Integrated Chinese and Western Medicine, No. 208 Yuehua Road, Gongbei, Xiangzhou District, Zhuhai 519000, Guangdong Province, China. sitalisa@163.com
Key Words	Electron transfer flavoprotein dehydrogenase mutation; Multiple acyl-CoA dehydrogenase deficiency; Multiple organ failure; Case report
Core Tip	Multiple acyl-CoA dehydrogenase deficiency (MADD) is a disease of rare autosomal recessive disorder of fatty acid, amino acid, and choline metabolism. Here, we report a severe case of a young man with onset type III MADD characterized by rhabdomyolysis and liver dysfunction. His urinary and serum analysis indicated organic acids, the elevation of several acylcarnitines and the reduction of carnitne. Eventually, we identified a rare compound heterozygous variant in the patient. Unfortunately, the patient was not responsive to riboflavin and progressively worsening into multiple organ failure that finally led to death.
Publish Date	2024-07-05 10:19
Citation	<p>Li XX, Yang XN, Pan HD, Liu L. Fatal multiple acyl-CoA dehydrogenase deficiency caused by ETFDH gene mutation: A case report. <i>World J Clin Cases</i> 2024; 12(23): 5422-5430</p>
URL	https://www.wjgnet.com/2307-8960/full/v12/i23/5422.htm
DOI	https://dx.doi.org/10.12998/wjcc.v12.i23.5422

Full Article (PDF)	WJCC-12-5422-with-cover.pdf
CARE Checklist–2016	95491-CARE-Checklist-2016.pdf
Manuscript File	95491-Review-FilipodiaCL.docx
Answering Reviewers	95491-answering-reviewers.pdf
Audio Core Tip	95491-audio.m4a
Conflict-of-Interest Disclosure Form	95491-conflict-of-interest-statement.pdf
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Non-Native Speakers of English Editing Certificate	95491-non-native-speakers.pdf
Peer-review Report	95491-peer-reviews.pdf
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Scientific Editor Work List	95491-scientific-editor-work-list.pdf
CrossCheck Report	95491-crosscheck-report.pdf