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Articles Published Processes
9/19/2024 8:21:14 AM | Browse: 61 | Download: 463
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Received |
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2024-04-14 15:38 |
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Peer-Review Started |
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2024-04-14 15:38 |
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To Make the First Decision |
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Return for Revision |
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2024-05-11 08:39 |
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Revised |
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2024-06-07 20:31 |
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Second Decision |
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2024-07-25 02:34 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-07-25 08:04 |
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Articles in Press |
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2024-07-25 08:04 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2024-08-03 14:47 |
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Typeset the Manuscript |
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2024-08-15 02:36 |
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Publish the Manuscript Online |
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2024-09-19 08:21 |
| ISSN |
2220-6124 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Basic Study |
| Article Title |
Protective effect of long-chain polyunsaturated fatty acids on the hepatorenal syndrome in rats
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| Manuscript Source |
Invited Manuscript |
| All Author List |
João Bruno Beretta Duailibe, Cassiana Macagnan Viau, Jenifer Saffi, Sabrina Alves Fernandes and Marilene Porawski |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Brazilian Agencies: Conselho Nacional de Desenvolvimento Científico e Tecnológico |
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| Programa Nacional de Cooperação Acadêmica/Coordenação de Aperfeiçoamento de Pessoal de Nível Superior |
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| Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul |
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| Corresponding Author |
Marilene Porawski, PhD, Adjunct Professor, Department of Hepatology and Basic Health Sciences, Federal University of Health Sciences of Porto Alegre, 245/308C, Porto Alegre 90050-170, Brazil. marilenep@ufcspa.edu.br |
| Key Words |
Long-chain polyunsaturated fatty acids; Antioxidant effect; Hepatorenal syndrome; Liver cirrhosis; Reactive oxygen species; Apoptosis |
| Core Tip |
Hepatorenal syndrome (HRS) is associated with a poor prognosis in individuals with advanced or decompensated cirrhosis. Palliative care involves the use of vasoconstrictor agents and intravenous albumin in combination. Currently, there are no effective treatments for this condition other than liver transplantation. Our research has shown that administering 1 g/kg of omega-3 to cirrhotic rats reduced oxidative damage, DNA damage, and apoptosis while enhancing antioxidant defenses and maintaining the kidney’s cellular integrity. These findings indicate that omega-3 supplementation could be complementary to managing HRS. |
| Publish Date |
2024-09-19 08:21 |
| Citation |
<p>Duailibe JBB, Viau CM, Saffi J, Fernandes SA, Porawski M. Protective effect of long-chain polyunsaturated fatty acids on the hepatorenal syndrome in rats. <i>World J Nephrol</i> 2024; 13(3): 95627</p> |
| URL |
https://www.wjgnet.com/2220-6124/full/v13/i3/95627.htm |
| DOI |
https://dx.doi.org/10.5527/wjn.v13.i3.95627 |
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