Publication Name	World Journal of Clinical Cases
Manuscript ID	95766
Country	United States

Received	2024-04-17 19:52
Peer-Review Started	2024-04-17 19:52
To Make the First Decision
Return for Revision	2024-06-13 03:33
Revised	2024-06-23 13:36
Second Decision	2024-07-12 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-07-15 02:59
Articles in Press	2024-07-15 02:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-07-19 06:47
Publish the Manuscript Online	2024-07-23 06:37

ISSN	2307-8960 (online)
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Category	Medicine, General & Internal
Manuscript Type	Letter to the Editor
Article Title	T lymphocyte proportion in Alzheimer’s disease prognosis
Manuscript Source	Invited Manuscript
All Author List	Matthew Willman, Gopi Patel and Brandon Lucke-Wold
ORCID	Author(s) ORCID Number Matthew Willman http://orcid.org/0000-0002-0388-2964 Brandon Lucke-Wold http://orcid.org/0000-0001-6577-4080
Funding Agency and Grant Number
Corresponding Author	Matthew Willman, N/A, N/A, N/A, College of Medicine, University of Florida, 1600 SW Archer Road, Gainesville, FL 32610, United States. matthewwillman@ufl.edu
Key Words	Alzheimer's disease; T lymphocyte; T lymphocyte proportion; Alzheimer's disease prognosis; Modified rankin scale; Immune cell count; Electroencephalogram; Immune function
Core Tip	Bai et al propose a novel marker for Alzheimer's disease (AD) prognosis: The proportion of T lymphocytes. In their single-center retrospective study, they found that a decrease in T lymphocyte proportion correlated with a poorer prognosis, as measured by the modified Rankin scale. This suggests T lymphocytes could serve as a predictive biomarker for AD prognosis. The study underscores the need for larger, multicenter investigations to validate these findings and highlights the potential of immune system dysregulation in AD progression, opening avenues for further research in understanding AD pathology and prognosis.
Publish Date	2024-07-23 06:37
Citation	<p>Willman M, Patel G, Lucke-Wold B. T lymphocyte proportion in Alzheimer’s disease prognosis. <i>World J Clin Cases</i> 2024; 12(26): 6001-6003</p>
URL	https://www.wjgnet.com/2307-8960/full/v12/i26/6001.htm
DOI	https://dx.doi.org/10.12998/wjcc.v12.i26.6001

Full Article (PDF)	WJCC-12-6001-with-cover.pdf
Manuscript File	95766_Auto_Edited_070707.docx
Answering Reviewers	95766-answering-reviewers.pdf
Audio Core Tip	95766-audio.mp3
Conflict-of-Interest Disclosure Form	95766-conflict-of-interest-statement.pdf
Copyright License Agreement	95766-copyright-assignment.pdf
Peer-review Report	95766-peer-reviews.pdf
Scientific Misconduct Check	95766-scientific-misconduct-check.png
Scientific Editor Work List	95766-scientific-editor-work-list.pdf
CrossCheck Report	95766-crosscheck-report.pdf
CrossCheck Report	95766-crosscheck-report.png