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Articles Published Processes
9/28/2024 4:34:25 AM | Browse: 122 | Download: 565
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Received |
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2024-04-19 02:29 |
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Peer-Review Started |
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2024-04-19 02:29 |
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First Decision by Editorial Office Director |
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2024-08-25 00:21 |
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Return for Revision |
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2024-08-25 10:51 |
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Revised |
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2024-08-30 07:56 |
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Publication Fee Transferred |
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2024-09-10 14:24 |
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Second Decision by Editor |
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2024-09-09 02:43 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2024-09-09 05:48 |
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Articles in Press |
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2024-09-09 05:48 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-09-19 06:30 |
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Publish the Manuscript Online |
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2024-09-28 04:34 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Case Report |
| Article Title |
Reassessment of palliative surgery in conversion therapy of previously unresectable hepatocellular carcinoma: Two case reports and review of literature
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yang-Bo Zhu, Jia-Yi Qin, Ting-Ting Zhang, Wen-Jin Zhang and Qi Ling |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Zhejiang Medical Science and Technology Project |
2023KY704 |
| Zhejiang Traditional Chinese Medicine Science and Technology Project |
2023ZR107, 2024ZF094 |
| Special Research Fund for Hospital Pharmacy of Zhejiang Pharmaceutical Association |
2021ZYY08 |
| Zhejiang Medical Association Clinical Research Fund |
2021ZYC-A64, 2021ZYC-A67 |
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| Corresponding Author |
Qi Ling, PhD, Chief Doctor, Chief Physician, Professor, Surgeon, Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. lingqi@zju.edu.cn |
| Key Words |
Hepatocellular carcinoma; Transarterial chemoembolization; Immunotherapy; Conversion Therapy; Tyrosine kinase inhibitors; Case report |
| Core Tip |
We herein present two successful cases of "conversion Therapy for unresectable hepatocellular carcinoma (HCC)" achieved mainly by palliative surgery combined with transarterial chemoembolization (TACE) plus immunotherapy and tyrosine kinase inhibitors. For some selected advanced HCC with a high risk of tumor overload and metastasis, if liver function permits, early palliative surgery combined with local subsequent TACE, along with targeted and immunotherapy, may be a tolerable and effective strategy, which may provide the opportunity for the ultimate cure for the initially unresectable HCC and effectively improve the long-term survival based on the promising prospects of combined targeted and immunotherapy. |
| Publish Date |
2024-09-28 04:34 |
| Citation |
Zhu YB, Qin JY, Zhang TT, Zhang WJ, Ling Q. Reassessment of palliative surgery in conversion therapy of previously unresectable hepatocellular carcinoma: Two case reports and review of literature. World J Gastrointest Surg 2024; 16(10): 3312-3320 |
| URL |
https://www.wjgnet.com/1948-9366/full/v16/i10/3312.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v16.i10.3312 |
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