| ISSN |
2220-3230 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Retrospective Study |
| Article Title |
SIMAP500: A novel risk score to identify recipients at higher risk of hepatocellular carcinoma recurrence following liver transplantation
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Amr Alnagar, Nekisa Zakeri, Konstantinos Koilias, Rosemary E Faulkes, Rachel Brown, Owen Cain, M Thamara P R Perera, Keith J Roberts, Rebeca Sanabria-Mateos, David C Bartlett, Yuk Ting Ma, Shivan Sivakumar, Shishir Shetty, Tahir Shah and Bobby V M Dasari |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Bobby V M Dasari, FRCS, Surgeon, Department of HBP and Liver Transplantation Surgery, Queen Elizabeth Hospital, University Hospitals Birmingham, Mindelsohn Way, Birmingham B15 2GW, United Kingdom. b.dasari@bham.ac.uk |
| Key Words |
Liver transplantation; Hepatocellular carcinoma; Recurrence; Survival |
| Core Tip |
Hepatocellular carcinoma recurrence following liver transplantation has a devastating effect on recipients’ survival. Different scoring systems were proposed to identify recipients at higher risk of recurrence. We used univariate and multivariate analysis to build a new scoring system [SIMAP500 (satellite nodules, increase in size, microvascular invasion, AFP > 500, poor differentiation)] and validated the novel scoring system using our cohort of liver transplant recipients. SIMAP500 has an excellent predictive power of recurrence and can be used to tailor post-transplant surveillance programs. |
| Publish Date |
2024-07-31 07:20 |
| Citation |
<p>Alnagar A, Zakeri N, Koilias K, Faulkes RE, Brown R, Cain O, Perera MTPR, Roberts KJ, Sanabria-Mateos R, Bartlett DC, Ma YT, Sivakumar S, Shetty S, Shah T, Dasari BVM. SIMAP500: A novel risk score to identify recipients at higher risk of hepatocellular carcinoma recurrence following liver transplantation. <i>World J Transplant</i> 2024; 14(3): 95849</p> |
| URL |
https://www.wjgnet.com/2220-3230/full/v14/i3/95849.htm |
| DOI |
https://dx.doi.org/10.5500/wjt.v14.i3.95849 |
