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9/29/2024 7:44:38 AM | Browse: 380 | Download: 1214
Publication Name World Journal of Methodology
Manuscript ID 95857
Country Türkiye
Received
2024-04-20 10:36
Peer-Review Started
2024-04-20 10:36
First Decision by Editorial Office Director
2024-05-28 07:03
Return for Revision
2024-05-28 07:03
Revised
2024-06-23 20:50
Publication Fee Transferred
Second Decision by Editor
2024-08-02 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2024-08-02 09:07
Articles in Press
2024-08-02 09:07
Edit the Manuscript by Language Editor
2024-08-07 23:06
Typeset the Manuscript
2024-08-19 00:54
Publish the Manuscript Online
2024-09-29 07:44
ISSN 2222-0682 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell & Tissue Engineering
Manuscript Type Clinical Trials Study
Article Title Advances in the treatment of autism spectrum disorder: Wharton jelly mesenchymal stem cell transplantation
Manuscript Source Invited Manuscript
All Author List Serdar Kabatas, Erdinç Civelek, Eyüp Can Savrunlu, Umut Karaaslan, Özlem Yıldız and Erdal Karaöz
ORCID
Author(s) ORCID Number
Serdar Kabatas http://orcid.org/0000-0003-2691-6861
Erdinç Civelek http://orcid.org/0000-0002-3988-4064
Eyüp Can Savrunlu http://orcid.org/0000-0001-9022-200X
Umut Karaaslan http://orcid.org/0000-0002-3267-6983
Özlem Yıldız http://orcid.org/0000-0002-1303-1645
Erdal Karaöz http://orcid.org/0000-0002-9992-833X
Funding Agency and Grant Number
Corresponding Author Serdar Kabatas, MD, Full Professor, Department of Neurosurgery, University of Health Sciences Turkey, Gaziosmanpaşa Training and Research Hospital, Karayolları Mahallesi, Osmanbey Caddesi 616. Sokak No. 10, Gaziosmanpaşa, Istanbul 34255, Türkiye. kabatasserdar@hotmail.com
Key Words Autism spectrum disorder; Neurorehabilitation; Stem cell transplantation; Wharton jelly mesenchymal cells
Core Tip According to the data of the World Health Organization, Autism Spectrum Disorder (ASD) is observed in approximately one in every hundred children. Recent studies have revealed that immune factors and inflammation are effective in the development of ASD. In this study, we applied 6 doses of Wharton's jelly-derived mesenchymal stem cell therapy to a 4-year-old patient diagnosed with autism spectrum disorder. After the applications, we observed the patient for 2 years. We did not encounter any serious side effects. According to Childhood Autism Rating Scale values and Denver II Developmental Screening Test values, we detected significant improvements.
Publish Date 2024-09-29 07:44
Citation

Kabatas S, Civelek E, Savrunlu EC, Karaaslan U, Yıldız Ö, Karaöz E. Advances in the treatment of autism spectrum disorder: Wharton jelly mesenchymal stem cell transplantation. World J Methodol 2025; 15(1): 95857

URL https://www.wjgnet.com/2222-0682/full/v15/i1/95857.htm
DOI https://dx.doi.org/10.5662/wjm.v15.i1.95857
Full Article (PDF) WJM-15-95857-with-cover.pdf