Publication Name	World Journal of Methodology
Manuscript ID	95857
Country	Türkiye

Received	2024-04-20 10:36
Peer-Review Started	2024-04-20 10:36
To Make the First Decision
Return for Revision	2024-05-28 07:03
Revised	2024-06-23 20:50
Second Decision	2024-08-02 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-08-02 09:07
Articles in Press	2024-08-02 09:07
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-08-07 23:06
Typeset the Manuscript	2024-08-19 00:54
Publish the Manuscript Online	2024-09-29 07:44

ISSN	2222-0682 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Cell & Tissue Engineering
Manuscript Type	Clinical Trials Study
Article Title	Advances in the treatment of autism spectrum disorder: Wharton jelly mesenchymal stem cell transplantation
Manuscript Source	Invited Manuscript
All Author List	Serdar Kabatas, Erdinç Civelek, Eyüp Can Savrunlu, Umut Karaaslan, Özlem Yıldız and Erdal Karaöz
ORCID	Author(s) ORCID Number Serdar Kabatas http://orcid.org/0000-0003-2691-6861 Erdinç Civelek http://orcid.org/0000-0002-3988-4064 Eyüp Can Savrunlu http://orcid.org/0000-0001-9022-200X Umut Karaaslan http://orcid.org/0000-0002-3267-6983 Özlem Yıldız http://orcid.org/0000-0002-1303-1645 Erdal Karaöz http://orcid.org/0000-0002-9992-833X
Funding Agency and Grant Number
Corresponding Author	Serdar Kabatas, MD, Full Professor, Department of Neurosurgery, University of Health Sciences Turkey, Gaziosmanpaşa Training and Research Hospital, Karayolları Mahallesi, Osmanbey Caddesi 616. Sokak No. 10, Gaziosmanpaşa, Istanbul 34255, Türkiye. kabatasserdar@hotmail.com
Key Words	Autism spectrum disorder; Neurorehabilitation; Stem cell transplantation; Wharton jelly mesenchymal cells
Core Tip	According to the data of the World Health Organization, Autism Spectrum Disorder (ASD) is observed in approximately one in every hundred children. Recent studies have revealed that immune factors and inflammation are effective in the development of ASD. In this study, we applied 6 doses of Wharton's jelly-derived mesenchymal stem cell therapy to a 4-year-old patient diagnosed with autism spectrum disorder. After the applications, we observed the patient for 2 years. We did not encounter any serious side effects. According to Childhood Autism Rating Scale values and Denver II Developmental Screening Test values, we detected significant improvements.
Publish Date	2024-09-29 07:44
Citation	<p>Kabatas S, Civelek E, Savrunlu EC, Karaaslan U, Yıldız Ö, Karaöz E. Advances in the treatment of autism spectrum disorder: Wharton jelly mesenchymal stem cell transplantation. <i>World J Methodol</i> 2025; 15(1): 95857</p>
URL	https://www.wjgnet.com/2222-0682/full/v15/i1/95857.htm
DOI	https://dx.doi.org/10.5662/wjm.v15.i1.95857

Full Article (PDF)	WJM-15-95857-with-cover.pdf
CONSORT 2010 Statement	95857-CONSORT-2010-statement.pdf
Manuscript File	95857_Auto_Edited_070302.docx
Answering Reviewers	95857-answering-reviewers.pdf
Audio Core Tip	95857-audio.mp3
Conflict-of-Interest Disclosure Form	95857-conflict-of-interest-statement.pdf
Copyright License Agreement	95857-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s)	95857-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate	95857-non-native-speakers.pdf
Video	95857-video.zip
Peer-review Report	95857-peer-reviews.pdf
Scientific Misconduct Check	95857-scientific-misconduct-check.png
Scientific Editor Work List	95857-scientific-editor-work-list.pdf
CrossCheck Report	95857-crosscheck-report.pdf
CrossCheck Report	95857-crosscheck-report.png