Publication Name	World Journal of Stem Cells
Manuscript ID	95933
Country	China

Received	2024-04-22 14:32
Peer-Review Started	2024-04-22 14:32
To Make the First Decision
Return for Revision	2024-08-15 05:56
Revised	2024-09-03 22:36
Second Decision	2024-10-06 01:25
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-10-18 09:36
Articles in Press	2024-10-18 09:36
Publication Fee Transferred	2024-10-22 10:35
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-11-04 06:03
Publish the Manuscript Online	2024-11-26 10:21

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Cell & Tissue Engineering
Manuscript Type	Basic Study
Article Title	Efficacy of serum-free cultured human umbilical cord mesenchymal stem cells in the treatment of knee osteoarthritis in mice
Manuscript Source	Unsolicited Manuscript
All Author List	Kai-Zhen Xiao, Gui Liao, Guang-Yu Huang, Yun-Long Huang and Rong-He Gu
ORCID	Author(s) ORCID Number Kai-Zhen Xiao http://orcid.org/0009-0003-1368-6427 Rong-He Gu http://orcid.org/0009-0008-6359-5706
Funding Agency and Grant Number	Funding Agency Grant Number Cultivated by Outstanding Young Scientific and Technological Innovation and Entrepreneurship Talents in Nanning City, China RC20210107 Self-Funded Research Project by Guangxi Health Commission, China Z20191090
Corresponding Author	Rong-He Gu, Doctor, Doctor, Doctor, Professor, Department of Orthopedic Surgery, The Fifth Affiliated Hospital of Guangxi Medical University, No. 89 Qixing Road, Qingxiu District, Nanning 530022, Guangxi Zhuang Autonomous Region, China. 201920518@sr.gxmu.edu.cn
Key Words	Osteoarthritis; Serum-free culture; Mesenchymal stem cell; Human umbilical cord mesenchymal stem cells; Serum-free culture of human umbilical cord mesenchymal stem cells; Hyaluronic acid
Core Tip	Mesenchymal stem cells have been shown to alleviate osteoarthritic cartilage and could therefore be used to treat osteoarthritis to reduce or delay the need for knee replacement therapy. This study provides a favorable foundation for the future application of serum-free cultured human umbilical cord mesenchymal stem cells in clinical trials for treating knee osteoarthritis.
Publish Date	2024-11-26 10:21
Citation	<p>Xiao KZ, Liao G, Huang GY, Huang YL, Gu RH. Efficacy of serum-free cultured human umbilical cord mesenchymal stem cells in the treatment of knee osteoarthritis in mice. <i>World J Stem Cells</i> 2024; 16(11): 944-955</p>
URL	https://www.wjgnet.com/1948-0210/full/v16/i11/944.htm
DOI	https://dx.doi.org/10.4252/wjsc.v16.i11.944

Full Article (PDF)	WJSC-16-944-with-cover.pdf
The ARRIVE Guidelines	95933-The-ARRIVE-Guidelines.pdf
Manuscript File	95933_Auto_Edited_033757.docx
Answering Reviewers	95933-answering-reviewers.pdf
Audio Core Tip	95933-audio.mp3
Biostatistics Review Certificate	95933-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	95933-conflict-of-interest-statement.pdf
Copyright License Agreement	95933-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	95933-foundation-statement.pdf
Institutional Animal Care and Use Committee Approval Form or Document	95933-institutional-animal-care-and-use-committee-statement.pdf
Non-Native Speakers of English Editing Certificate	95933-non-native-speakers.pdf
Peer-review Report	95933-peer-reviews.pdf
Scientific Misconduct Check	95933-scientific-misconduct-check.png
Scientific Editor Work List	95933-scientific-editor-work-list.pdf
CrossCheck Report	95933-crosscheck-report.pdf