Publication Name	World Journal of Clinical Cases
Manuscript ID	95940
Country	United States

Received	2024-04-22 15:16
Peer-Review Started	2024-04-22 15:16
To Make the First Decision
Return for Revision	2024-08-09 06:11
Revised	2024-08-18 06:44
Second Decision	2024-08-21 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-08-21 07:55
Articles in Press	2024-08-21 07:55
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-08-22 08:50
Publish the Manuscript Online	2024-09-04 06:40

ISSN	2307-8960 (online)
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Category	Clinical Neurology
Manuscript Type	Minireviews
Article Title	Overview of emerging therapies for demyelinating diseases
Manuscript Source	Invited Manuscript
All Author List	Robert Medina, Ann-Marie Derias, Maria Lakdawala, Skye Speakman and Brandon Lucke-Wold
ORCID	Author(s) ORCID Number Robert Medina http://orcid.org/0009-0004-1811-6105 Brandon Lucke-Wold http://orcid.org/0000-0001-6577-4080
Funding Agency and Grant Number
Corresponding Author	Robert Medina, N/A, N/A, N/A, University of Florida College of Medicine, University of Florida, 1600 SE Archer Road, Gainesville, Fl 32610, United States. medina.robert@ufl.edu
Key Words	Central nervous system disease; Autoimmune; Remyelination; Demyelination; Myelin; Oligodendrocyte; Emerging therapies; Multiple Sclerosis
Core Tip	Autoimmune disorders of the nervous system still pose a significant therapeutic challenge. Current treatments focus on symptom management but no cure exists. Since many of these disorders are caused by demyelination, it follows that remyelination may be key in finding a cure. Promising new research focuses on the use of endogenous cellular and inflammatory mediators to induce remyelination in patients with demyelinating diseases. These efforts may culminate in treatments such as stem cell transplantation and signaling pathway manipulation. In addition to these systemic therapies, nerve guide conduits have shown promise in aiding the recovery of peripheral nerve injuries.
Publish Date	2024-09-04 06:40
Citation	<p>Medina R, Derias AM, Lakdawala M, Speakman S, Lucke-Wold B. Overview of emerging therapies for demyelinating diseases. <i>World J Clin Cases</i> 2024; 12(30): 6361-6373</p>
URL	https://www.wjgnet.com/2307-8960/full/v12/i30/6361.htm
DOI	https://dx.doi.org/10.12998/wjcc.v12.i30.6361

Full Article (PDF)	WJCC-12-6361-with-cover.pdf
Manuscript File	95940_Auto_Edited_005858.docx
Answering Reviewers	95940-answering-reviewers.pdf
Audio Core Tip	95940-audio.m4a
Conflict-of-Interest Disclosure Form	95940-conflict-of-interest-statement.pdf
Copyright License Agreement	95940-copyright-assignment.pdf
Peer-review Report	95940-peer-reviews.pdf
Scientific Misconduct Check	95940-scientific-misconduct-check.png
Scientific Editor Work List	95940-scientific-editor-work-list.pdf
CrossCheck Report	95940-crosscheck-report.pdf
CrossCheck Report	95940-crosscheck-report.png