| ISSN |
2220-315x (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Oncometabolites in Pancreatic Cancer: Strategies and Its Implications
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Arunima Maiti, Susmita Mondal, Sounetra Choudhury, Arnab Bandopadhyay, Sanghamitra Mukherjee and Nilabja Sikdar |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Department of Biotechnology, Government of India, Ramalingaswami Re-entry Fellowship |
RLS/BT/Re-entry/05/2012 |
| Department of Higher, Education, Science & Technology and Biotechnology, Government of West Bengal, India |
BT/P/Budget/RD-37/2016 |
|
| Corresponding Author |
Nilabja Sikdar, PhD, Doctor, Doctor, Researcher, Human Genetics Unit, Indian Statistical Institute, 203, BT Road, Kolkata 700108, West Bengal, India. snilabja@gmail.com |
| Key Words |
Metabolic reprogramming; Pancreatic cancer; Metabolic symbiosis; Therapy resistance; Anti-pancreatic cancer therapy |
| Core Tip |
Pancreatic cancer is supported by reprogrammed metabolism. Cancer specific glucose, glutamine, fat, nucleotide metabolism and inter-metabolite communication between tumor and stroma, impart continual proliferation, therapy resistance, and immunosuppression. Key enzymes and intermediates of altered metabolic pathways would help to formulate disease specific markers and therapeutic approaches. This review sums up reformed metabolic pathways in PanCa to formulate detection and remedial strategies for better disease management. |
| Publish Date |
2024-10-31 07:40 |
| Citation |
<p>Maiti A, Mondal S, Choudhury S, Bandopadhyay A, Mukherjee S, Sikdar N. Oncometabolites in Pancreatic Cancer: Strategies and Its Implications. <i>World J Exp Med</i> 2024; 14(4): 96005</p> |
| URL |
https://www.wjgnet.com/2220-315x/full/v14/i4/96005.htm |
| DOI |
https://dx.doi.org/10.5493/wjem.v14.i4.96005 |
