Publication Name	World Journal of Gastroenterology
Manuscript ID	9605
Country	Japan

Received	2014-02-20 06:16
Peer-Review Started	2014-02-20 08:38
First Decision by Editorial Office Director
Return for Revision	2014-03-20 08:44
Revised	2014-04-14 21:39
Publication Fee Transferred
Second Decision by Editor	2014-05-19 15:20
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2014-05-19 15:30
Articles in Press	2014-05-23 10:22
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-07-29 14:31
Publish the Manuscript Online	2014-08-18 16:49

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Phenol-based endoscopic ultrasound-guided celiac plexus neurolysis for East Asian alcohol-intolerant upper gastrointestinal cancer patients: A pilot study
Manuscript Source	Unsolicited Manuscript
All Author List	Hirotoshi Ishiwatari, Tsuyoshi Hayashi, Makoto Yoshida, Michihiro Ono, Hiroyuki Masuko, Tsutomu Sato, Koji Miyanishi, Yasushi Sato, Rishu Takimoto, Masayoshi Kobune, Atsushi Miyamoto, Tomoko Sonoda and Junji Kato
Funding Agency and Grant Number
Corresponding Author	Hirotoshi Ishiwatari, MD, PhD, Assistant Professor, Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo 060-8543, Japan. ishihiro481019@gmail.com
Key Words	Celiac plexus neurolysis; Celiac plexus blockade; Endoscopic ultrasound; Phenol; Pain management; Upper gastrointestinal cancer
Core Tip	We compared the pain-relieving effect and complications between endoscopic ultrasound-guided celiac plexus neurolysis (EUS-CPN) using phenol on patients intolerant to alcohol and ethanol on patients without alcohol intolerance. Phenol had similar pain-relieving effects to ethanol; using phenol can avoid burning pain and inebriation complications. To date, few data regarding phenol-based EUS-CPN exist, and it is generally believed that phenol has a slightly slower onset and shorter duration of action than ethanol. Consequently, phenol is not routinely used in EUS-CPN. However, approximately half of East Asians lack mitochondrial aldehyde dehydrogenase activity, which causes alcohol intolerance. Our data provide evidence on phenol-based EUS-CPN for patients with alcohol intolerance.
Publish Date	2014-08-18 16:49
Citation	Ishiwatari H, Hayashi T, Yoshida M, Ono M, Masuko H, Sato T, Miyanishi K, Sato Y, Takimoto R, Kobune M, Miyamoto A, Sonoda T, Kato J. Phenol-based endoscopic ultrasound-guided celiac plexus neurolysis for East Asian alcohol-intolerant upper gastrointestinal cancer patients: A pilot study. World J Gastroenterol 2014; 20(30): 10512-10517
URL	http://www.wjgnet.com/1007-9327/full/v20/i30/10512.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i30.10512

Full Article (PDF)	WJG-20-10512.pdf
Full Article (Word)	WJG-20-10512.doc
Manuscript File	9605-Review.docx
Answering Reviewers	9605-Answering reviewers.pdf
Copyright License Agreement	9605-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	9605-Language certificate.pdf
Peer-review Report	9605-Peer review.pdf