| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Phenol-based endoscopic ultrasound-guided celiac plexus neurolysis for East Asian alcohol-intolerant upper gastrointestinal cancer patients: A pilot study
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hirotoshi Ishiwatari, Tsuyoshi Hayashi, Makoto Yoshida, Michihiro Ono, Hiroyuki Masuko, Tsutomu Sato, Koji Miyanishi, Yasushi Sato, Rishu Takimoto, Masayoshi Kobune, Atsushi Miyamoto, Tomoko Sonoda and Junji Kato |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Hirotoshi Ishiwatari, MD, PhD, Assistant Professor, Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo 060-8543, Japan. ishihiro481019@gmail.com |
| Key Words |
Celiac plexus neurolysis; Celiac plexus blockade; Endoscopic ultrasound; Phenol; Pain management; Upper gastrointestinal cancer |
| Core Tip |
We compared the pain-relieving effect and complications between endoscopic ultrasound-guided celiac plexus neurolysis (EUS-CPN) using phenol on patients intolerant to alcohol and ethanol on patients without alcohol intolerance. Phenol had similar pain-relieving effects to ethanol; using phenol can avoid burning pain and inebriation complications. To date, few data regarding phenol-based EUS-CPN exist, and it is generally believed that phenol has a slightly slower onset and shorter duration of action than ethanol. Consequently, phenol is not routinely used in EUS-CPN. However, approximately half of East Asians lack mitochondrial aldehyde dehydrogenase activity, which causes alcohol intolerance. Our data provide evidence on phenol-based EUS-CPN for patients with alcohol intolerance. |
| Publish Date |
2014-08-18 16:49 |
| Citation |
Ishiwatari H, Hayashi T, Yoshida M, Ono M, Masuko H, Sato T, Miyanishi K, Sato Y, Takimoto R, Kobune M, Miyamoto A, Sonoda T, Kato J. Phenol-based endoscopic ultrasound-guided celiac plexus neurolysis for East Asian alcohol-intolerant upper gastrointestinal cancer patients: A pilot study. World J Gastroenterol 2014; 20(30): 10512-10517 |
| URL |
http://www.wjgnet.com/1007-9327/full/v20/i30/10512.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v20.i30.10512 |
