Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	96127
Country	Greece

Received	2024-04-27 15:32
Peer-Review Started	2024-04-27 15:32
To Make the First Decision
Return for Revision	2024-07-05 21:06
Revised	2024-07-18 19:31
Second Decision	2024-07-24 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-07-24 06:47
Articles in Press	2024-07-24 06:47
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-07-25 17:44
Typeset the Manuscript	2024-10-18 03:39
Publish the Manuscript Online	2024-10-30 14:58

ISSN	1948-9366 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: Https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Editorial
Article Title	Pembrolizumab in patients with gastric cancer and liver metastases: A paradigm shift in immunotherapy
Manuscript Source	Invited Manuscript
All Author List	Grigorios Christodoulidis, Dimitra Bartzi, Konstantinos Eleftherios Koumarelas and Marina Nektaria Kouliou
ORCID	Author(s) ORCID Number Grigorios Christodoulidis http://orcid.org/0000-0003-3413-0666 Konstantinos Eleftherios Koumarelas http://orcid.org/0000-0002-5614-4770 Marina Nektaria Kouliou http://orcid.org/0000-0002-2055-2297
Funding Agency and Grant Number
Corresponding Author	Grigorios Christodoulidis, MD, PhD, Academic Editor, Department of General Surgery, The University Hospital of Larissa, The University of Thessaly, Biopolis Campus, Larissa 41110, Greece. gregsurg09@gmail.com
Key Words	Gastric cancer; Immunotherapy; Pembrolizumab; Liver metastasis; Prognosis; Treatment
Core Tip	Given the multifaceted challenges of treating gastric cancer with liver metastases, adopting a personalized approach to therapy is crucial. This involves integrating biomarker testing, such as programmed cell death ligand 1 expression, into treatment decisions to identify likely responders to immunotherapy like pembrolizumab. By tailoring treatment strategies based on individual patient characteristics and disease biology, clinicians can optimize therapeutic efficacy and mitigate potential adverse events, ultimately improving outcomes for patients navigating this complex clinical scenario.
Publish Date	2024-10-30 14:58
Citation	<p>Christodoulidis G, Bartzi D, Koumarelas KE, Kouliou MN. Pembrolizumab in patients with gastric cancer and liver metastases: A paradigm shift in immunotherapy. <i>World J Gastrointest Surg</i> 2024; 16(11): 3391-3394</p>
URL	https://www.wjgnet.com/1948-9366/full/v16/i11/3391.htm
DOI	https://dx.doi.org/10.4240/wjgs.v16.i11.3391

Full Article (PDF)	WJGS-16-3391-with-cover.pdf
Manuscript File	96127_Auto_Edited_032059.docx
Answering Reviewers	96127-answering-reviewers.pdf
Audio Core Tip	96127-audio.m4a
Conflict-of-Interest Disclosure Form	96127-conflict-of-interest-statement.pdf
Copyright License Agreement	96127-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	96127-non-native-speakers.pdf
Peer-review Report	96127-peer-reviews.pdf
Scientific Misconduct Check	96127-scientific-misconduct-check.png
Scientific Editor Work List	96127-scientific-editor-work-list.pdf
CrossCheck Report	96127-crosscheck-report.pdf