Publication Name	World Journal of Hepatology
Manuscript ID	96128
Country	Italy

Received	2024-04-27 17:36
Peer-Review Started	2024-04-28 01:29
To Make the First Decision
Return for Revision	2024-05-16 09:04
Revised	2024-05-28 08:03
Second Decision	2024-06-18 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-06-18 09:11
Articles in Press	2024-06-18 09:11
Publication Fee Transferred	2024-07-12 13:02
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-07-31 13:28
Publish the Manuscript Online	2024-08-21 23:22

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Successful treatment of acute liver failure due to Wilson’s disease: Serendipity or fortuity?
Manuscript Source	Unsolicited Manuscript
All Author List	Valeria Delle Cave, Fabiola Di Dato, Pier Luigi Calvo, Maria Immacolata Spagnuolo and Raffaele Iorio
ORCID	Author(s) ORCID Number Fabiola Di Dato http://orcid.org/0000-0001-9915-8972 Maria Immacolata Spagnuolo http://orcid.org/0000-0001-5396-4944 Raffaele Iorio http://orcid.org/0000-0002-7483-234X
Funding Agency and Grant Number
Corresponding Author	Raffaele Iorio, MD, Associate Professor, Department of Translational Medical Science, Section of Pediatrics, University of Naples Federico II, Via Pansini 5, Naples 80131, Italy. riorio@unina.it
Key Words	Fulminant liver failure; Copper; Chelator; Zinc; Steroids; Liver transplantation; Autoimmune hepatitis; Prognostic score; 24 hour-urinary copper excretion; Native liver
Core Tip	There is no firm recommendation on the management of acute liver failure due to Wilson's disease, for which liver transplantation is the only reliable treatment option. The retrospective study highlights the successful treatment of a patient with an unconventional low-dose therapy of D-penicillamine and zinc plus steroids with the aim of opening new perspectives in the management of the condition, stimulating a critical evaluation on the topic and thus promoting the use of all possible therapeutic opportunities to increase survival with the native liver.
Publish Date	2024-08-21 23:22
Citation	<p>Delle Cave V, Di Dato F, Calvo PL, Spagnuolo MI, Iorio R. Successful treatment of acute liver failure due to Wilson’s disease: Serendipity or fortuity? <i>World J Hepatol</i> 2024; 16(8): 1111-1119</p>
URL	https://www.wjgnet.com/1948-5182/full/v16/i8/1111.htm
DOI	https://dx.doi.org/10.4254/wjh.v16.i8.1111

Full Article (PDF)	WJH-16-1111-with-cover.pdf
Manuscript File	96128_Auto_Edited_071105.docx
Answering Reviewers	96128-answering-reviewers.pdf
Audio Core Tip	96128-audio.m4a
Biostatistics Review Certificate	96128-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	96128-conflict-of-interest-statement.pdf
Copyright License Agreement	96128-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s)	96128-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	96128-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	96128-non-native-speakers.pdf
Peer-review Report	96128-peer-reviews.pdf
Scientific Misconduct Check	96128-scientific-misconduct-check.jpg
Scientific Editor Work List	96128-scientific-editor-work-list.pdf
CrossCheck Report	96128-crosscheck-report.pdf