BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
12/9/2024 10:39:55 AM | Browse: 34 | Download: 140
 |
Received |
|
2024-04-29 08:14 |
|
Peer-Review Started |
|
2024-04-29 08:14 |
 |
To Make the First Decision |
|
|
|
Return for Revision |
|
2024-08-24 05:41 |
|
Revised |
|
2024-09-05 14:31 |
|
Second Decision |
|
2024-10-12 02:44 |
|
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2024-10-12 06:34 |
|
Articles in Press |
|
2024-10-12 06:34 |
|
Publication Fee Transferred |
|
2024-10-16 03:53 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2024-10-25 06:13 |
|
Publish the Manuscript Online |
|
2024-12-09 10:39 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Basic Study |
| Article Title |
Effects of Bifidobacterium lactis BLa80 on fecal and mucosal flora and stem cell factor/c-kit signaling pathway in simulated microgravity rats
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ping Zhang, Ying Zhu, Pu Chen, Tong Zhou, Zhe-Yi Han, Jun Xiao, Jian-Feng Ma, Wen Ma, Peng Zang and Ying Chen |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Ying Chen, PhD, Associate Professor, Department of Gastroenterology, The Air Force Medical Center, No. 30 Fucheng Road, Haidian District, Beijing 100142, China. cy20020910@163.com |
| Key Words |
Simulated microgravity; Rat; Intestinal flora; Gastrointestinal motility; Stem cell factor/c-kit signaling pathway |
| Core Tip |
Previous studies have found that the simulated microgravity environment can cause gastrointestinal motility disorders in rats, but the mechanism is not clear. Considering that changes in intestinal mechanical barrier and biological barrier as well as stem cell factor (SCF)/c-kit signaling pathway related to Cajal stromal cells are closely related to gastrointestinal motility, we used protein molecular biology tests and bioinformatics methods to identify the effects and mechanisms of simulated microgravity environment on gastrointestinal motility in rats. And the effect of Bifidobacterium lactis (B. lactis) BLa80 after intervention. This study demonstrated for the first time that B. lactis BLa80 may affect the changes of gastrointestinal motility by improving intestinal mucosal barrier, improving intestinal flora dysregulation, and up-regulating SCF/c-kit signaling pathway. |
| Publish Date |
2024-12-09 10:39 |
| Citation |
<p>Zhang P, Zhu Y, Chen P, Zhou T, Han ZY, Xiao J, Ma JF, Ma W, Zang P, Chen Y. Effects of Bifidobacterium lactis BLa80 on fecal and mucosal flora and stem cell factor/c-kit signaling pathway in simulated microgravity rats. <i>World J Gastroenterol</i> 2025; 31(1): 96199</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i1/96199.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i1.96199 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
