Publication Name	World Journal of Stem Cells
Manuscript ID	96227
Country	China

Received	2024-04-30 03:06
Peer-Review Started	2024-04-30 03:06
To Make the First Decision
Return for Revision	2024-09-18 05:37
Revised	2024-09-26 00:32
Second Decision	2024-10-31 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-10-31 10:08
Articles in Press	2024-10-31 10:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-11-15 12:45
Publish the Manuscript Online	2024-11-26 10:21

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Cell Biology
Manuscript Type	Letter to the Editor
Article Title	Resilience and challenges: Evaluating the impact of stress conditions on mesenchymal stem cells across different passages
Manuscript Source	Invited Manuscript
All Author List	Yue Ding, Fang Lin and Xiao-Ting Liang
ORCID	Author(s) ORCID Number Xiao-Ting Liang http://orcid.org/0000-0003-3262-1859
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81500207 Pyramid Talent Project YQ677
Corresponding Author	Xiao-Ting Liang, MD, PhD, Institute for Regenerative Medicine, Shanghai East Hospital, School of Life Sciences and Technology, Tongji University, No. 150 Jimo Road, Shanghai 200120, China. liangxt@tongji.edu.cn
Key Words	Mesenchymal stem cells; High glucose; Hypoxia; Cellular senescence; Passages
Core Tip	This article discussed the research by Almahasneh et al on the resilience of mesenchymal stem cells (MSCs) under high glucose and severe hypoxia conditions at different passages. Highlighting the adaptability of higher passage MSCs, this study challenges traditional preferences for lower passage MSCs for use in clinical treatments, especially under conditions simulating diabetic or ischemic environments. While offering novel insights into MSC adaptability are offered, the research’s reliance on in vitro tests from a single cell line highlights the need for more in-depth in vivo studies to ascertain the clinical relevance of these findings and broaden their applicability.
Publish Date	2024-11-26 10:21
Citation	<p>Ding Y, Lin F, Liang XT. Resilience and challenges: Evaluating the impact of stress conditions on mesenchymal stem cells across different passages. <i>World J Stem Cells</i> 2024; 16(11): 974-977</p>
URL	https://www.wjgnet.com/1948-0210/full/v16/i11/974.htm
DOI	https://dx.doi.org/10.4252/wjsc.v16.i11.974

Full Article (PDF)	WJSC-16-974-with-cover.pdf
Manuscript File	96227_Auto_Edited_025839.docx
Answering Reviewers	96227-answering-reviewers.pdf
Audio Core Tip	96227-audio.mp3
Conflict-of-Interest Disclosure Form	96227-conflict-of-interest-statement.pdf
Copyright License Agreement	96227-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	96227-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	96227-non-native-speakers.pdf
Peer-review Report	96227-peer-reviews.pdf
Scientific Misconduct Check	96227-scientific-misconduct-check.png
Scientific Editor Work List	96227-scientific-editor-work-list.pdf
CrossCheck Report	96227-crosscheck-report.pdf