| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Contribution of extracellular vesicles to steatosis-related liver disease and their therapeutic potential
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Margarita Montoya-Buelna, Inocencia G Ramirez-Lopez, Cesar A San Juan-Garcia, Jose J Garcia-Regalado, Mariana S Millan-Sanchez, Ulises de la Cruz-Mosso, Jesse Haramati, Ana L Pereira-Suarez and Jose Macias-Barragan |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Universidad de Guadalajara, Programa de Apoyo a la Mejora en las Condiciones de Producción de los Miembros del SNI y SNCA |
PROSNI 2024 |
| Universidad de Guadalajara, Programa de Impulso a la Investigación |
PIN 2020 |
| Secretaría de Salud de México, Dirección General de Calidad y Educación en Salud |
Fellowship 2022-2023 |
|
| Corresponding Author |
Jose Macias-Barragan, PhD, Researcher, Departamento de Ciencias de la Salud, Centro Universitario de los Valles, Universidad de Guadalajara, Carretera Guadalajara - Ameca Km 45.5, Ameca 46600, Jalisco, Mexico. josemacias@valles.udg.mx |
| Key Words |
Extracellular vesicles; Exosomes; Chronic liver disease; Hepatocellular carcinoma; Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis |
| Core Tip |
Extracellular vesicles are tiny particles released by cells, and transport specific molecules from one cell to another, resulting in the sending of a message. Chronic liver diseases are mainly induced by cirrhosis, liver cancer, viral hepatitis, along with obesity. Alterations in hepatic lipid metabolism, as fat accumulation in liver cells, can trigger lipotoxicity events that prompt extracellular vesicles release leading to inflammation. In this context, we aim to provide a comprehensive overview of extracellular vesicles, covering their definition, types, and biogenesis, with emphasis on extracellular vesicles associated with steatosis-related liver disease, diagnosis, treatment, and its possible therapeutic applications. |
| Publish Date |
2024-09-23 10:30 |
| Citation |
<p>Montoya-Buelna M, Ramirez-Lopez IG, San Juan-Garcia CA, Garcia-Regalado JJ, Millan-Sanchez MS, de la Cruz-Mosso U, Haramati J, Pereira-Suarez AL, Macias-Barragan J. Contribution of extracellular vesicles to steatosis-related liver disease and their therapeutic potential. <i>World J Hepatol</i> 2024; 16(9): 1211-1228</p> |
| URL |
https://www.wjgnet.com/1948-5182/full/v16/i9/1211.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v16.i9.1211 |
