Publication Name	World Journal of Orthopedics
Manuscript ID	96774
Country	South Korea

Received	2024-05-15 03:11
Peer-Review Started	2024-05-15 03:11
To Make the First Decision
Return for Revision	2024-07-09 09:18
Revised	2024-07-17 10:35
Second Decision	2024-07-26 02:33
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-07-26 08:19
Articles in Press	2024-07-26 08:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-08-05 00:25
Publish the Manuscript Online	2024-08-13 09:40

ISSN	2218-5836 (online)
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Category	Hematology
Manuscript Type	Case Report
Article Title	Hemophagocytic lymphohistiocytosis triggered by relapsing polychondritis: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Mi-Ran Han, Jeong-Hwan Hwang, Seungah Cha, So-Yeon Jeon, Kyu Yun Jang, Namsu Kim and Chang-Hoon Lee
ORCID	Author(s) ORCID Number Mi-Ran Han http://orcid.org/0009-0009-7714-9835 Jeong-Hwan Hwang http://orcid.org/0000-0003-2114-1374 Seungah Cha http://orcid.org/0009-0005-1534-8979 So-Yeon Jeon http://orcid.org/0000-0002-4792-5049 Kyu Yun Jang http://orcid.org/0000-0002-5276-4446 Namsu Kim http://orcid.org/0000-0003-3147-5634 Chang-Hoon Lee http://orcid.org/0000-0002-1317-4646
Funding Agency and Grant Number
Corresponding Author	Chang-Hoon Lee, MD, PhD, Assistant Professor, Doctor, Doctor, Department of Internal Medicine, Jeonbuk National University Medical School, 20 Geonji-ro, Jeonju 54907, South Korea. rednose2000@hanmail.net
Key Words	Hemophagocytic lymphohistiocytosis; Relapsing polychondritis; Autoimmune disease; Fever of unknown origin; Steroid; Case report
Core Tip	Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening condition typically triggered in adults by conditions such as cancer, infections, and autoimmune disorders, resulting in immune system over-activation. Relapsing polychondritis (RP), an uncommon disease, is diagnosed through physical examination. In contrast to primary HLH, which necessitates stem cell transplantation is the only definitive cure, acquired HLH can be managed with therapies such as chemotherapy and immunosuppressive therapy, tailored to the underlying cause. The patient received treatment for HLH using RP therapies and was successfully cured with methylprednisolone (1 mg/kg) and azathioprine.
Publish Date	2024-08-13 09:40
Citation	<p>Han MR, Hwang JH, Cha S, Jeon SY, Jang KY, Kim N, Lee CH. Hemophagocytic lymphohistiocytosis triggered by relapsing polychondritis: A case report. <i>World J Orthop</i> 2024; 15(8): 813-819</p>
URL	https://www.wjgnet.com/2218-5836/full/v15/i8/813.htm
DOI	https://dx.doi.org/10.5312/wjo.v15.i8.813

Full Article (PDF)	WJO-15-813-with-cover.pdf
CARE Checklist–2016	96774-CARE-Checklist-2016.pdf
Manuscript File	96774_Auto_Edited_072718.docx
Answering Reviewers	96774-answering-reviewers.pdf
Audio Core Tip	96774-audio.mp3
Conflict-of-Interest Disclosure Form	96774-conflict-of-interest-statement.pdf
Copyright License Agreement	96774-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s)	96774-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate	96774-non-native-speakers.pdf
Peer-review Report	96774-peer-reviews.pdf
Scientific Misconduct Check	96774-scientific-misconduct-check.png
Scientific Editor Work List	96774-scientific-editor-work-list.pdf
CrossCheck Report	96774-crosscheck-report.png
CrossCheck Report	96774-crosscheck-report.pdf