Publication Name	World Journal of Hepatology
Manuscript ID	96825
Country	China

Received	2024-05-15 23:42
Peer-Review Started	2024-05-15 23:42
To Make the First Decision
Return for Revision	2024-06-18 09:43
Revised	2024-07-13 05:42
Second Decision	2024-08-02 02:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-08-02 07:14
Articles in Press	2024-08-02 07:14
Publication Fee Transferred	2024-08-06 02:21
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-08-12 00:57
Publish the Manuscript Online	2024-08-21 23:22

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Gadoxetic acid-enhanced magnetic resonance imaging in the assessment of hepatic sinusoidal obstruction syndrome in a mouse model
Manuscript Source	Unsolicited Manuscript
All Author List	Yuan-Yuan Chen, Li Yang, Jun Li, Sheng-Xiang Rao, Ying Ding and Meng-su Zeng
ORCID	Author(s) ORCID Number Yuan-Yuan Chen http://orcid.org/0000-0003-2342-145X Sheng-Xiang Rao http://orcid.org/0000-0001-7722-8327 Ying Ding http://orcid.org/0000-0002-4478-3436
Funding Agency and Grant Number	Funding Agency Grant Number the National Science Foundation for Young Scientists of China 81701682
Corresponding Author	Ying Ding, MD, Associate Chief Physician, Department of Radiology, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Xuhui District, Shanghai 200032, China. ding.ying@zs-hospital.sh.cn
Key Words	T1 mapping; Gadoxetic acid; Sinusoidal obstruction syndrome; Organic anion transporter polypeptides; Magnetic resonance imaging
Core Tip	Neoadjuvant chemotherapy could cause hepatic sinusoidal obstruction syndrome (SOS) in colorectal liver metastases patients and increases postoperative morbidity and mortality. We used a mouse model of monocrotaline-induced hepatic SOS. We confirmed the relationship between magnetic resonance imaging (MRI) parameters T1 relaxation time 20 minutes after enhancement, a reduction in T1 relaxation time and first enhancement slope percentage of the liver parenchyma and hepatic SOS, suggesting a potential method for the assessment of hepatic SOS. Our results also demonstrated that MRI parameters were correlated with organic anion transporter polypeptide 1 levels.
Publish Date	2024-08-21 23:22
Citation	<p>Chen YY, Yang L, Li J, Rao SX, Ding Y, Zeng MS. Gadoxetic acid-enhanced magnetic resonance imaging in the assessment of hepatic sinusoidal obstruction syndrome in a mouse model. <i>World J Hepatol</i> 2024; 16(8): 1167-1176</p>
URL	https://www.wjgnet.com/1948-5182/full/v16/i8/1167.htm
DOI	https://dx.doi.org/10.4254/wjh.v16.i8.1167

Full Article (PDF)	WJH-16-1167-with-cover.pdf
The ARRIVE Guidelines	96825-The-ARRIVE-Guidelines.pdf
Manuscript File	96825_Auto_Edited_064023.docx
Answering Reviewers	96825-answering-reviewers.pdf
Audio Core Tip	96825-audio.mp3
Biostatistics Review Certificate	96825-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	96825-conflict-of-interest-statement.pdf
Copyright License Agreement	96825-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	96825-foundation-statement.pdf
Institutional Animal Care and Use Committee Approval Form or Document	96825-institutional-animal-care-and-use-committee-statement.pdf
Non-Native Speakers of English Editing Certificate	96825-non-native-speakers.pdf
Peer-review Report	96825-peer-reviews.pdf
Scientific Misconduct Check	96825-scientific-misconduct-check.png
Scientific Editor Work List	96825-scientific-editor-work-list.pdf
CrossCheck Report	96825-crosscheck-report.png
CrossCheck Report	96825-crosscheck-report.pdf