Publication Name	World Journal of Clinical Cases
Manuscript ID	96876
Country	South Korea

Received	2024-05-17 11:48
Peer-Review Started	2024-05-17 11:48
To Make the First Decision
Return for Revision	2024-09-15 05:31
Revised	2024-10-15 21:19
Second Decision	2024-10-24 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-10-24 10:35
Articles in Press	2024-10-24 10:35
Publication Fee Transferred	2024-10-20 10:47
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-10-31 08:30
Publish the Manuscript Online	2024-11-08 03:51

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: Https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Case Report
Article Title	Pan-TRK positive uterine sarcoma in immunohistochemistry without neurotrophic tyrosine receptor kinase gene fusions: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Seungmee Lee, Yu-Ra Jeon, Changmin Shin, Sun-Young Kwon and Sojin Shin
ORCID	Author(s) ORCID Number Seungmee Lee http://orcid.org/0000-0003-1405-2656 Sojin Shin http://orcid.org/0000-0002-7432-6025
Funding Agency and Grant Number	Funding Agency Grant Number Grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute, funded by the Ministry of Health & Welfare, Republic of Korea RS-2022-KH129889
Corresponding Author	Sojin Shin, MD, PhD, Professor, Department of Obstetrics and Gynecology, Keimyung University School of Medicine, 1035 Dalgubeol-daero, Dalseo-gu, Daegu 42601, South Korea. hope2014@dsmc.or.kr
Key Words	Uterine sarcoma; Cervical sarcoma; Neurotrophic tyrosine receptor kinase gene fusion; Next generation sequencing; Case report
Core Tip	This case report highlights a rare malignant mesenchymal tumor originating from the uterine cervix that was pan-TRK immunohistochemistry-positive but lacked neurotrophic tyrosine receptor kinase (NTRK) gene fusions. Although NTRK-fusion sarcomas are aggressive and may benefit from targeted TRK inhibitor therapy, this case underscores the importance of molecular genetic diagnostics to guide accurate treatment decisions. The report contributes to the limited literature on NTRK-positive uterine sarcomas and emphasizes the potential clinical value of TRK inhibitors in selected cases.
Publish Date	2024-11-08 03:51
Citation	<p>Lee S, Jeon YR, Shin C, Kwon SY, Shin S. Pan-TRK positive uterine sarcoma in immunohistochemistry without neurotrophic tyrosine receptor kinase gene fusions: A case report. <i>World J Clin Cases</i> 2025; 13(2): 96876</p>
URL	https://www.wjgnet.com/2307-8960/full/v13/i2/96876.htm
DOI	https://dx.doi.org/10.12998/wjcc.v13.i2.96876

Full Article (PDF)	WJCC-13-96876-with-cover.pdf
CARE Checklist–2016	96876-CARE-Checklist-2016.pdf
Manuscript File	96876_Auto_Edited_012743.docx
Answering Reviewers	96876-answering-reviewers.pdf
Audio Core Tip	96876-audio.mp3
Conflict-of-Interest Disclosure Form	96876-conflict-of-interest-statement.pdf
Copyright License Agreement	96876-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	96876-foundation-statement.pdf
Signed Consent for Treatment Form(s) or Document(s)	96876-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate	96876-non-native-speakers.pdf
Peer-review Report	96876-peer-reviews.pdf
Scientific Editor Work List	96876-scientific-editor-work-list.pdf
CrossCheck Report	96876-crosscheck-report.pdf