Publication Name	World Journal of Clinical Oncology
Manuscript ID	97007
Country	China

Received	2024-08-19 08:40
Peer-Review Started	2024-05-20 15:11
To Make the First Decision
Return for Revision	2024-09-20 12:22
Revised	2024-10-04 10:13
Second Decision	2024-11-04 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-11-04 08:20
Articles in Press	2024-11-04 08:20
Publication Fee Transferred	2024-11-06 12:13
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-12-06 00:39
Publish the Manuscript Online	2024-12-11 10:19

ISSN	2218-4333 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Molecular mechanism of pancreatic ductal adenocarcinoma: The heterogeneity of cancer-associated fibroblasts and key signaling pathways
Manuscript Source	Unsolicited Manuscript
All Author List	Zhong-Yuan Hu, Ding Ding, Yu Song, Ya-Feng Deng, Cheng-Ming Zhang and Tao Yu
ORCID	Author(s) ORCID Number Zhong-Yuan Hu http://orcid.org/0009-0002-3403-5490 Tao Yu http://orcid.org/0009-0003-3892-302X
Funding Agency and Grant Number	Funding Agency Grant Number National Key Research and Development Program Project 2017YFC1700601 Shaanxi Provincial Key Research and Development Program Project 2018SF-350 Leading Talents in Scientific and Technological Innovation of the Shaanxi Province Special Support Plan 646
Corresponding Author	Tao Yu, Digestive Department I, Shaanxi Provincial Hospital of Traditional Chinese Medicine, No. 4 Ming Palace Road, Lianhu District, Xi’an 710000, Shaanxi Province, China. yt0745@163.com
Key Words	Pancreatic cancer; Fibroblasts; Signaling pathways; Tumor microenvironment
Core Tip	This research explored the mechanisms of action of fibroblasts in pancreatic tumors and revealed their effects on the tumor microenvironment. This study revealed that fibroblasts enhance tumor growth and metastasis through specific signaling pathways, suggesting that targeting fibroblasts may emerge as a new strategy for treating pancreatic cancer.
Publish Date	2024-12-11 10:19
Citation	<p>Hu ZY, Ding D, Song Y, Deng YF, Zhang CM, Yu T. Molecular mechanism of pancreatic ductal adenocarcinoma: The heterogeneity of cancer-associated fibroblasts and key signaling pathways. <i>World J Clin Oncol</i> 2025; 16(2): 97007</p>
URL	https://www.wjgnet.com/2218-4333/full/v16/i2/97007.htm
DOI	https://dx.doi.org/10.5306/wjco.v16.i2.97007

Full Article (PDF)	WJCO-16-97007-with-cover.pdf
Manuscript File	97007_Auto_Edited_014311.docx
Answering Reviewers	97007-answering-reviewers.pdf
Audio Core Tip	97007-audio.m4a
Conflict-of-Interest Disclosure Form	97007-conflict-of-interest-statement.pdf
Copyright License Agreement	97007-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	97007-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	97007-non-native-speakers.pdf
Peer-review Report	97007-peer-reviews.pdf
Scientific Misconduct Check	97007-scientific-misconduct-check.png
Scientific Editor Work List	97007-scientific-editor-work-list.pdf
CrossCheck Report	97007-crosscheck-report.pdf