Publication Name	World Journal of Radiology
Manuscript ID	97037
Country	Japan

Received	2024-05-21 05:24
Peer-Review Started	2024-05-21 05:25
To Make the First Decision
Return for Revision	2024-07-03 06:03
Revised	2024-07-08 05:09
Second Decision	2024-07-10 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-07-10 05:50
Articles in Press	2024-07-10 05:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-07-15 01:19
Publish the Manuscript Online	2024-07-24 02:56

ISSN	1949-8470 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Medicine, Research & Experimental
Manuscript Type	Retrospective Study
Article Title	Correlation between dose-volume parameters and rectal bleeding after 12 fractions of carbon ion radiotherapy for prostate cancer
Manuscript Source	Invited Manuscript
All Author List	Takashi Ono, Hiraku Sato, Yuya Miyasaka, Yasuhito Hagiwara, Natsuko Yano, Hiroko Akamatsu, Mayumi Harada and Mayumi Ichikawa
ORCID	Author(s) ORCID Number Takashi Ono http://orcid.org/0000-0002-9711-1158 Hiraku Sato http://orcid.org/0000-0002-0210-3439 Yasuhito Hagiwara http://orcid.org/0000-0002-5612-5094 Natsuko Yano http://orcid.org/0000-0002-2911-8489 Hiroko Akamatsu http://orcid.org/0000-0001-8086-8974 Mayumi Ichikawa http://orcid.org/0000-0001-8092-3371
Funding Agency and Grant Number
Corresponding Author	Takashi Ono, MD, PhD, Doctor, Doctor, Department of Radiation Oncology, Faculty of Medicine, Yamagata University, 2-2-2 Iida-Nishi, Yamagata 990-9585, Japan. abc1123513@gmail.com
Key Words	Carbon ion radiotherapy; Prostate cancer; Rectal bleeding; Dose volume parameters; Prevention
Core Tip	This study identified the risk factors for rectal bleeding, including dose–volume parameters of 51.6 Gy [relative biological effectiveness (RBE)] in 12 fractions of carbon ion radiotherapy (CIRT) for prostate cancer. The cutoff values of D2cc = 46.46 Gy (RBE), V10 Gy (RBE) = 9.85 cc, and V20 Gy (RBE) = 7.00 cc were significant factors for the occurrence rate of grade 2 rectal bleeding. When planning CIRT for prostate cancer, the rate of rectal bleeding may decrease if these values are used.
Publish Date	2024-07-24 02:56
Citation	<p>Ono T, Sato H, Miyasaka Y, Hagiwara Y, Yano N, Akamatsu H, Harada M, Ichikawa M. Correlation between dose-volume parameters and rectal bleeding after 12 fractions of carbon ion radiotherapy for prostate cancer. <i>World J Radiol</i> 2024; 16(7): 256-264</p>
URL	https://www.wjgnet.com/1949-8470/full/v16/i7/256.htm
DOI	https://dx.doi.org/10.4329/wjr.v16.i7.256

Full Article (PDF)	WJR-16-256-with-cover.pdf
Manuscript File	97037_Auto_Edited_072929.docx
Answering Reviewers	97037-answering-reviewers.pdf
Audio Core Tip	97037-audio.mp3
Biostatistics Review Certificate	97037-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	97037-conflict-of-interest-statement.pdf
Copyright License Agreement	97037-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s)	97037-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	97037-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	97037-non-native-speakers.pdf
Peer-review Report	97037-peer-reviews.pdf
Scientific Misconduct Check	97037-scientific-misconduct-check.png
Scientific Editor Work List	97037-scientific-editor-work-list.pdf
CrossCheck Report	97037-crosscheck-report.pdf