| ISSN |
1949-8462 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Clinical and Translational Research |
| Article Title |
Treatment of chronic heart failure with spleen qi-deficiency syndrome by Chinese herbal compound prescriptions for invigorating the spleen
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Si-Qi Li, Dong-Yu Min, Jun-Wen Jiang, Xiao-Ying Li, Xu-Na Yang, Wen-Bo Gu, Jia-Hui Jiang, Li-Hao Chen, Han Nan and Ze-Yu Chen |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Shenyang Municipal Science and Technology Bureau, 2021 Shenyang Science and Technology Program-Public Health R&D Special Project (Joint Project) |
21-174-9-04 |
|
| Corresponding Author |
Si-Qi Li, MD, Chief Physician, Department of Cardiology II, The Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, No. 33 Beiling Street, Huanggu District, Shenyang 110000, Liaoning Province, China. pangdun66@163.com |
| Key Words |
Invigorate the spleen; Resolve phlegm and remove blood stasis; Traditional Chinese medicine; Chronic heart failure; Data mining; Network pharmacology; Bioinformatics; Confirmatory research; Spleen-qi deficiency syndrome |
| Core Tip |
According to the clinical characteristics of patients, the dialectical treatment mainly adopts the treatment methods of strengthening Qi and nourishing Yin, promoting blood circulation and removing blood stasis, resolving phlegm and removing water, warming and tonifying heart yang. In this study, the authors found that the Chinese medicine compound for invigorating the spleen, removing phlegm and removing blood stasis can treat chronic heart failure by influencing the mitochondrial structure of cardiomyocytes, oxidative emergency, energy metabolism and other functions and pathways. |
| Publish Date |
2024-07-24 13:09 |
| Citation |
Li SQ, Min DY, Jiang JW, Li XY, Yang XN, Gu WB, Jiang JH, Chen LH, Nan H, Chen ZY. Treatment of chronic heart failure with spleen qi-deficiency syndrome by Chinese herbal compound prescriptions for invigorating the spleen. World J Cardiol 2024; 16(7): 422-435 |
| URL |
https://www.wjgnet.com/1949-8462/full/v16/i7/422.htm |
| DOI |
https://dx.doi.org/10.4330/wjc.v16.i7.422 |
