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10/25/2024 10:27:33 AM | Browse: 57 | Download: 194
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 97118
Country China
Received
2024-08-01 08:13
Peer-Review Started
2024-08-01 08:13
To Make the First Decision
Return for Revision
2024-08-19 10:18
Revised
2024-09-11 09:02
Second Decision
2024-09-29 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2024-09-29 08:12
Articles in Press
2024-09-29 08:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2024-10-11 12:52
Publish the Manuscript Online
2024-10-25 10:27
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Basic Study
Article Title Impact and mechanism study of dioscin on biological characteristics of colorectal cancer cells
Manuscript Source Unsolicited Manuscript
All Author List Xie-Xiao Cai, Zhen-Feng Huang, Fu-Yang Tu and Jie Yu
ORCID
Author(s) ORCID Number
Jie Yu http://orcid.org/0009-0004-2578-016X
Funding Agency and Grant Number
Corresponding Author Jie Yu, BMed, N/A, N/A, Department of Gastrointestinal Surgery, The Third Affiliated Hospital of Wenzhou Medical University, No. 108 Wansong Road, Wenzhou 325200, Zhejiang Province, China. 15968760998@163.com
Key Words Dioscin; Colorectal cancer; Notch1; Cell apoptosis; Cell proliferation
Core Tip This study investigates the anticancer effects of dioscin on colorectal cancer (CRC) cells (HCT116). Our findings reveal that dioscin inhibits cell viability, promotes apoptosis, and suppresses migration and invasion by modulating the Notch1 signaling pathway. These results highlight the potential of dioscin as a therapeutic agent against CRC.
Publish Date 2024-10-25 10:27
Citation <p>Cai XX, Huang ZF, Tu FY, Yu J. Impact and mechanism study of dioscin on biological characteristics of colorectal cancer cells. <i>World J Gastrointest Oncol</i> 2024; 16(11): 4456-4467</p>
URL https://www.wjgnet.com/1948-5204/full/v16/i11/4456.htm
DOI https://dx.doi.org/10.4251/wjgo.v16.i11.4456
Full Article (PDF) WJGO-16-4456-with-cover.pdf
Manuscript File 97118_Auto_Edited_095530.docx
Answering Reviewers 97118-answering-reviewers.pdf
Audio Core Tip 97118-audio.mp3
Biostatistics Review Certificate 97118-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 97118-conflict-of-interest-statement.pdf
Copyright License Agreement 97118-copyright-assignment.pdf
Institutional Review Board Approval Form or Document 97118-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 97118-non-native-speakers.pdf
Peer-review Report 97118-peer-reviews.pdf
Scientific Misconduct Check 97118-scientific-misconduct-check.png
Scientific Editor Work List 97118-scientific-editor-work-list.pdf
CrossCheck Report 97118-crosscheck-report.png
CrossCheck Report 97118-crosscheck-report.pdf