Publication Name	World Journal of Diabetes
Manuscript ID	97211
Country	China

Received	2024-05-29 11:44
Peer-Review Started	2024-05-29 11:44
To Make the First Decision
Return for Revision	2024-06-22 19:45
Revised	2024-06-29 14:25
Second Decision	2024-07-15 03:20
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-07-23 07:22
Articles in Press	2024-07-23 07:22
Publication Fee Transferred	2024-07-28 15:22
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-07-31 13:27
Publish the Manuscript Online	2024-08-27 15:11

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Cell Biology
Manuscript Type	Basic Study
Article Title	Bone marrow-derived mesenchymal stem cell-derived exosome-loaded miR-129-5p targets high-mobility group box 1 attenuates neurological-impairment after diabetic cerebral hemorrhage
Manuscript Source	Unsolicited Manuscript
All Author List	Yue-Ying Wang, Ke Li, Jia-Jun Wang, Wei Hua, Qi Liu, Yu-Lan Sun, Ji-Ping Qi and Yue-Jia Song
ORCID	Author(s) ORCID Number Yue-Ying Wang http://orcid.org/0000-0002-4898-3187 Ji-Ping Qi http://orcid.org/0000-0001-8025-9781 Yue-Jia Song http://orcid.org/0000-0002-8919-7801
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81900743 Heilongjiang Province Outstanding Young Medical Talents Training Grant Project, China HYD2020YQ0007
Corresponding Author	Yue-Jia Song, MD, Professor, Department of Endocrinology, First Clinical Hospital, Harbin Medical University, No. 23 Youzheng Street, Nangang District, Harbin 150001, Heilongjiang Province, China. songyuejia@126.com
Key Words	Bone marrow mesenchymal stem cells; Exosome; Diabetic cerebral hemorrhage; Neuroinflammation; MicroRNA-129-5p; High mobility group box 1
Core Tip	Diabetic intracerebral hemorrhage is a serious complication of diabetes. In this study, we investigated the effect of exosomes derived from bone marrow-derived mesenchymal stem cells on the attenuation of neuroinflammation and neurological impairment after comorbid cerebral hemorrhage and diabetes. We also explored the specific mechanisms through which they perform their functions. Overall, we hypothesized that bone marrow-derived mesenchymal stem cell exosomes could afford a novel remedy in the treatment of cerebral hemorrhage in patients with diabetes.
Publish Date	2024-08-27 15:11
Citation	<p>Wang YY, Li K, Wang JJ, Hua W, Liu Q, Sun YL, Qi JP, Song YJ. Bone marrow-derived mesenchymal stem cell-derived exosome-loaded miR-129-5p targets high-mobility group box 1 attenuates neurological-impairment after diabetic cerebral hemorrhage. <i>World J Diabetes</i> 2024; 15(9): 1979-2001</p>
URL	https://www.wjgnet.com/1948-9358/full/v15/i9/1979.htm
DOI	https://dx.doi.org/10.4239/wjd.v15.i9.1979

Full Article (PDF)	WJD-15-1979-with-cover.pdf
The ARRIVE Guidelines	97211-The-ARRIVE-Guidelines.pdf
Manuscript File	97211_Auto_Edited_064757.docx
Answering Reviewers	97211-answering-reviewers.pdf
Audio Core Tip	97211-audio.mp3
Biostatistics Review Certificate	97211-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	97211-conflict-of-interest-statement.pdf
Copyright License Agreement	97211-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	97211-foundation-statement.pdf
Institutional Animal Care and Use Committee Approval Form or Document	97211-institutional-animal-care-and-use-committee-statement.pdf
Non-Native Speakers of English Editing Certificate	97211-non-native-speakers.pdf
Supplementary Material	97211-supplementary-material.pdf
Peer-review Report	97211-peer-reviews.pdf
Journal Editor-in-Chief Review Report	97211-journal-editor-in-chief.pdf
Scientific Misconduct Check	97211-scientific-misconduct-check.png
Scientific Editor Work List	97211-scientific-editor-work-list.pdf
CrossCheck Report	97211-crosscheck-report.pdf