Publication Name	World Journal of Diabetes
Manuscript ID	97336
Country	Thailand

Received	2024-07-31 01:43
Peer-Review Started	2024-05-28 08:48
To Make the First Decision
Return for Revision	2024-10-30 08:20
Revised	2024-11-11 04:54
Second Decision	2024-12-17 07:05
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-12-25 10:17
Articles in Press	2024-12-25 10:17
Publication Fee Transferred	2024-11-14 02:47
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-01-07 06:01
Publish the Manuscript Online	2025-01-21 09:26

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Research & Experimental Medicine
Manuscript Type	Basic Study
Article Title	Glabridin and gymnemic acid alleviates choroid structural change and choriocapillaris impairment in diabetic rat’s eyes
Manuscript Source	Unsolicited Manuscript
All Author List	Udomlak Massathit, Manaras Komolkriengkrai and Wipapan Khimmaktong
ORCID	Author(s) ORCID Number Wipapan Khimmaktong http://orcid.org/0000-0002-7899-0118
Funding Agency and Grant Number	Funding Agency Grant Number Prince of Songkla University Research Fund No. SCI6302040S
Corresponding Author	Wipapan Khimmaktong, Associate Professor, PhD, Department of Anatomy, Division of Health and Applied Sciences, Faculty of Science, Prince of Songkla University, Kanjanavanich Road, Kohong, Hat Yai 90110, Songkhla, Thailand. wipapan.k@psu.ac.th
Key Words	Diabetes; Choroid; Gymnemic acid; Glabridin; Vascular endothelial growth factor; Cluster of differentiation 31; Choriocapillaris
Core Tip	To investigate the effects of glabridin and gymnemic acid on the choroidal layer and choriocapillaris in diabetic rats’ eyes, as well as the expression of vascular endothelial growth factor and cluster of differentiation 31. Five groups were created out of the Wistar rats. In the diabetic group, there was an increase in the thickness of both the choroid layer and the wall of the arteries as well as choroidal impairment. The choroidal thickness, and the walls of the choroid arteries in diabetic rats treated with glabridin 40 mg/kg body weight, the diabetic rats treated with gymnemic acid 400 mg/kg body weight, and the diabetic rats treated with glyburide 4 mg/kg body weight groups all rose. When compared to the group with diabetes, the expression of vascular endothelial growth factor and cluster of differentiation 31 was shown to be lower.
Publish Date	2025-01-21 09:26
Citation	<p>Massathit U, Komolkriengkrai M, Khimmaktong W. Glabridin and gymnemic acid alleviates choroid structural change and choriocapillaris impairment in diabetic rat’s eyes. <i>World J Diabetes</i> 2025; 16(3): 97336</p>
URL	https://www.wjgnet.com/1948-9358/full/v16/i3/97336.htm
DOI	https://dx.doi.org/10.4239/wjd.v16.i3.97336

Full Article (PDF)	WJD-16-97336-with-cover.pdf
The ARRIVE Guidelines	97336-The-ARRIVE-Guidelines.pdf
Manuscript File	97336_Auto_Edited_022925.docx
Answering Reviewers	97336-answering-reviewers.pdf
Audio Core Tip	97336-audio.m4a
Biostatistics Review Certificate	97336-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	97336-conflict-of-interest-statement.pdf
Copyright License Agreement	97336-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	97336-foundation-statement.pdf
Institutional Animal Care and Use Committee Approval Form or Document	97336-institutional-animal-care-and-use-committee-statement.pdf
Non-Native Speakers of English Editing Certificate	97336-non-native-speakers.pdf
Peer-review Report	97336-peer-reviews.pdf
Journal Editor-in-Chief Review Report	97336-journal-editor-in-chief.pdf
Scientific Misconduct Check	97336-scientific-misconduct-check.png
Scientific Editor Work List	97336-scientific-editor-work-list.pdf
CrossCheck Report	97336-crosscheck-report.png
CrossCheck Report	97336-crosscheck-report.pdf