Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	97497
Country	China

Received	2024-05-31 10:07
Peer-Review Started	2024-05-31 10:07
To Make the First Decision
Return for Revision	2024-06-21 04:19
Revised	2024-07-03 06:37
Second Decision	2024-07-19 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-07-19 06:07
Articles in Press	2024-07-19 06:07
Publication Fee Transferred	2024-07-19 07:31
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-07-31 05:00
Publish the Manuscript Online	2024-09-09 08:41

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Case Report
Article Title	Two different mutational types of familial gastrointestinal stromal tumors: Two case reports
Manuscript Source	Unsolicited Manuscript
All Author List	Xiao-Ke Wang, Lu-Fan Shen, Xin Yang, He Su, Tao Wu, Peng-Xian Tao, Hong-Ying Lv, Tong-Han Yao, Lin Yi and Yuan-Hui Gu
ORCID	Author(s) ORCID Number Xiao-Ke Wang http://orcid.org/0009-0003-5734-1762 Tong-Han Yao http://orcid.org/0009-0001-6779-7996 Yuan-Hui Gu http://orcid.org/0000-0003-0364-3012
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 82160842 Clinical Research Project of Research Fund of Gansu Provincial Hospital 23GSSYD-17 General Program of the Joint Scientific Research Fund 23JRRA1521
Corresponding Author	Yuan-Hui Gu, MD, Chief Doctor, Surgeon, Surgical Oncologist, Department of General Surgery, Gansu Provincial Hospital, No. 204 Donggang West Road, Lanzhou 730000, Gansu Province, China. guyuanh@163.com
Key Words	Gastrointestinal stromal tumor; Familial gastrointestinal stromal tumor; Wild-type gastrointestinal stromal tumors; PDGFRA; Imatinib; Treatment; Case report
Core Tip	Familial gastrointestinal stromal tumors (GISTs) include primary familial GISTs with predominantly KIT/PDGFRA mutations and wild-type GISTs; however, there are no reports on whether there are different types of GISTs in the same genetic family. We report two cases of GISTs in the same family with different types of mutations. During our long-term follow-up, the favorable prognosis of these patients verified the accuracy of our treatment strategy. We also improved the whole process of diagnosis and treatment of familial GISTs in order to better manage this rare familial disease.
Publish Date	2024-09-09 08:41
Citation	<p>Wang XK, Shen LF, Yang X, Su H, Wu T, Tao PX, Lv HY, Yao TH, Yi L, Gu YH. Two different mutational types of familial gastrointestinal stromal tumors: Two case reports. <i>World J Gastrointest Oncol</i> 2024; 16(9): 4028-4036</p>
URL	https://www.wjgnet.com/1948-5204/full/v16/i9/4028.htm
DOI	https://dx.doi.org/10.4251/wjgo.v16.i9.4028

Full Article (PDF)	WJGO-16-4028-with-cover.pdf
CARE Checklist–2016	97497-CARE-Checklist-2016.pdf
Manuscript File	97497_Auto_Edited_022817.docx
Answering Reviewers	97497-answering-reviewers.pdf
Audio Core Tip	97497-audio.m4a
Conflict-of-Interest Disclosure Form	97497-conflict-of-interest-statement.pdf
Copyright License Agreement	97497-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	97497-foundation-statement.pdf
Signed Consent for Treatment Form(s) or Document(s)	97497-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate	97497-non-native-speakers.pdf
Peer-review Report	97497-peer-reviews.pdf
Scientific Misconduct Check	97497-scientific-misconduct-check.png
Scientific Editor Work List	97497-scientific-editor-work-list.pdf
CrossCheck Report	97497-crosscheck-report.png
CrossCheck Report	97497-crosscheck-report.pdf