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9/9/2024 8:41:21 AM | Browse: 62 | Download: 164
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 97604
Country China
Received
2024-06-03 14:00
Peer-Review Started
2024-06-03 14:00
To Make the First Decision
Return for Revision
2024-07-23 06:03
Revised
2024-07-31 11:45
Second Decision
2024-08-12 05:15
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2024-08-12 10:05
Articles in Press
2024-08-12 10:05
Publication Fee Transferred
2024-08-12 11:51
Edit the Manuscript by Language Editor
Typeset the Manuscript
2024-08-20 04:24
Publish the Manuscript Online
2024-09-09 08:41
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Retrospective Study
Article Title Impact of baseline steroids on the efficacy of neoadjuvant immunochemotherapy in locally advanced esophageal squamous cell carcinoma
Manuscript Source Unsolicited Manuscript
All Author List Yuan-Heng Huang, Guo-Zhen Yang, Hui-Guo Chen, Xiao-Jun Li, Yong-Hui Wu, Kai Zhang, Jian-Nan Xu and Jian Zhang
ORCID
Author(s) ORCID Number
Yuan-Heng Huang http://orcid.org/0000-0003-3357-8645
Yong-Hui Wu http://orcid.org/0000-0003-2392-1382
Kai Zhang http://orcid.org/0000-0003-3905-5095
Jian Zhang http://orcid.org/0000-0001-5000-6142
Funding Agency and Grant Number
Corresponding Author Jian Zhang, MD, PhD, Chief Doctor, Department of Cardiothoracic Surgery, The Third Affiliated Hospital of Sun Yat-sen University, No. 600 Tianhe Road, Guangzhou 510630, Guangdong Province, China. sumszhangjian@163.com
Key Words Esophageal squamous cell carcinoma; Neoadjuvant immunochemotherapy; Dexamethasone; Antihistamines; Treatment efficacy
Core Tip This study evaluated the impact of baseline corticosteroid use on the outcomes of neoadjuvant immunochemotherapy (nIC) in patients with locally advanced esophageal squamous cell carcinoma (ESCC). These findings indicate that low-dose dexamethasone or antihistamines can be used for pretreatment without compromising short-term or long-term efficacy. Notably, administering 20 mg of dexamethasone before nIC significantly improved progression-free survival in ESCC patients, highlighting the potential benefit of optimizing the corticosteroid dose in clinical practice. These results support further investigations in larger, prospective trials.
Publish Date 2024-09-09 08:41
Citation <p>Huang YH, Yang GZ, Chen HG, Li XJ, Wu YH, Zhang K, Xu JN, Zhang J. Impact of baseline steroids on the efficacy of neoadjuvant immunochemotherapy in locally advanced esophageal squamous cell carcinoma. <i>World J Gastrointest Oncol</i> 2024; 16(9): 3887-3897</p>
URL https://www.wjgnet.com/1948-5204/full/v16/i9/3887.htm
DOI https://dx.doi.org/10.4251/wjgo.v16.i9.3887
Full Article (PDF) WJGO-16-3887-with-cover.pdf
Manuscript File 97604_Auto_Edited_013535.docx
Answering Reviewers 97604-answering-reviewers.pdf
Audio Core Tip 97604-audio.mp3
Biostatistics Review Certificate 97604-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 97604-conflict-of-interest-statement.pdf
Copyright License Agreement 97604-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 97604-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 97604-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 97604-non-native-speakers.pdf
Peer-review Report 97604-peer-reviews.pdf
Scientific Misconduct Check 97604-scientific-misconduct-check.png
Scientific Editor Work List 97604-scientific-editor-work-list.pdf
CrossCheck Report 97604-crosscheck-report.pdf
CrossCheck Report 97604-crosscheck-report.png