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Articles Published Processes
9/9/2024 8:41:21 AM | Browse: 62 | Download: 164
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Received |
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2024-06-03 14:00 |
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Peer-Review Started |
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2024-06-03 14:00 |
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To Make the First Decision |
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Return for Revision |
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2024-07-23 06:03 |
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Revised |
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2024-07-31 11:45 |
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Second Decision |
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2024-08-12 05:15 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-08-12 10:05 |
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Articles in Press |
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2024-08-12 10:05 |
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Publication Fee Transferred |
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2024-08-12 11:51 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-08-20 04:24 |
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Publish the Manuscript Online |
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2024-09-09 08:41 |
ISSN |
1948-5204 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Oncology |
Manuscript Type |
Retrospective Study |
Article Title |
Impact of baseline steroids on the efficacy of neoadjuvant immunochemotherapy in locally advanced esophageal squamous cell carcinoma
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Yuan-Heng Huang, Guo-Zhen Yang, Hui-Guo Chen, Xiao-Jun Li, Yong-Hui Wu, Kai Zhang, Jian-Nan Xu and Jian Zhang |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Jian Zhang, MD, PhD, Chief Doctor, Department of Cardiothoracic Surgery, The Third Affiliated Hospital of Sun Yat-sen University, No. 600 Tianhe Road, Guangzhou 510630, Guangdong Province, China. sumszhangjian@163.com |
Key Words |
Esophageal squamous cell carcinoma; Neoadjuvant immunochemotherapy; Dexamethasone; Antihistamines; Treatment efficacy |
Core Tip |
This study evaluated the impact of baseline corticosteroid use on the outcomes of neoadjuvant immunochemotherapy (nIC) in patients with locally advanced esophageal squamous cell carcinoma (ESCC). These findings indicate that low-dose dexamethasone or antihistamines can be used for pretreatment without compromising short-term or long-term efficacy. Notably, administering 20 mg of dexamethasone before nIC significantly improved progression-free survival in ESCC patients, highlighting the potential benefit of optimizing the corticosteroid dose in clinical practice. These results support further investigations in larger, prospective trials. |
Publish Date |
2024-09-09 08:41 |
Citation |
<p>Huang YH, Yang GZ, Chen HG, Li XJ, Wu YH, Zhang K, Xu JN, Zhang J. Impact of baseline steroids on the efficacy of neoadjuvant immunochemotherapy in locally advanced esophageal squamous cell carcinoma. <i>World J Gastrointest Oncol</i> 2024; 16(9): 3887-3897</p> |
URL |
https://www.wjgnet.com/1948-5204/full/v16/i9/3887.htm |
DOI |
https://dx.doi.org/10.4251/wjgo.v16.i9.3887 |
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