Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	97644
Country	China

Received	2024-06-04 15:06
Peer-Review Started	2024-06-04 15:06
To Make the First Decision
Return for Revision	2024-11-24 07:11
Revised	2024-12-09 08:35
Second Decision	2025-01-15 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-01-15 08:08
Articles in Press	2025-01-15 08:08
Publication Fee Transferred	2024-12-10 00:58
Edit the Manuscript by Language Editor	2025-01-20 21:42
Typeset the Manuscript	2025-03-05 02:35
Publish the Manuscript Online	2025-03-25 16:18

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Cell Biology
Manuscript Type	Basic Study
Article Title	Snail family transcriptional repressor 1 radiosensitizes esophageal cancer via epithelial-mesenchymal transition signaling: From bioinformatics to integrated study
Manuscript Source	Unsolicited Manuscript
All Author List	Xiao-Li Lv, Qi-Liang Peng, Xin-Peng Wang, Zhi-Chao Fu, Jian-Ping Cao, Jian Wang, Li-Li Wang and Yang Jiao
ORCID	Author(s) ORCID Number Xiao-Li Lv http://orcid.org/0009-0004-9509-6400 Zhi-Chao Fu http://orcid.org/0000-0001-8096-3496 Jian Wang http://orcid.org/0000-0002-1255-9928 Li-Li Wang http://orcid.org/0000-0001-9816-6524 Yang Jiao http://orcid.org/0000-0002-5452-5553
Funding Agency and Grant Number	Funding Agency Grant Number National key R&D Program of China 2022YFC2503700 and 2022YFC2503703 National Health Commission Key Laboratory of Nuclear Technology Medical Transformation (Mianyang Central Hospital) 2023HYX005
Corresponding Author	Yang Jiao, PhD, Professor, State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions, Soochow University, No. 199 Ren'ai Road, Suzhou Industrial Park, Suzhou 215123, Jiangsu Province, China. jiaoyang@suda.edu.cn
Key Words	Esophageal cancer; Radiosensitivity; Snail family transcriptional repressor 1; Bioinformatics; Epithelial-mesenchymal transition
Core Tip	Snail family transcriptional repressor 1 (SNAI1) significantly affects both radiosensitivity and epithelial-mesenchymal transition in esophageal cancer (ESCA), validated by a combination of bioinformatics, clinical data, and experimental studies. Its pivotal role in tumor progression and patient survival suggests that targeting SNAI1 may offer novel strategies to enhance the effectiveness of radiotherapy in ESCA treatment.
Publish Date	2025-03-25 16:18
Citation	<p>Lv XL, Peng QL, Wang XP, Fu ZC, Cao JP, Wang J, Wang LL, Jiao Y. Snail family transcriptional repressor 1 radiosensitizes esophageal cancer via epithelial-mesenchymal transition signaling: From bioinformatics to integrated study. <i>World J Gastrointest Oncol</i> 2025; 17(4): 97644</p>
URL	https://www.wjgnet.com/1948-5204/full/v17/i4/97644.htm
DOI	https://dx.doi.org/10.4251/wjgo.v17.i4.97644

Full Article (PDF)	WJGO-17-97644-with-cover.pdf
The ARRIVE Guidelines	97644-The-ARRIVE-Guidelines.pdf
Manuscript File	97644_Auto_Edited_140804.docx
Answering Reviewers	97644-answering-reviewers.pdf
Audio Core Tip	97644-audio.mp3
Biostatistics Review Certificate	97644-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	97644-conflict-of-interest-statement.pdf
Copyright License Agreement	97644-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	97644-foundation-statement.pdf
Institutional Animal Care and Use Committee Approval Form or Document	97644-institutional-animal-care-and-use-committee-statement.pdf
Institutional Review Board Approval Form or Document	97644-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	97644-non-native-speakers.pdf
Peer-review Report	97644-peer-reviews.pdf
Scientific Misconduct Check	97644-scientific-misconduct-check.png
Scientific Editor Work List	97644-scientific-editor-work-list.pdf
CrossCheck Report	97644-crosscheck-report.pdf