Publication Name	World Journal of Cardiology
Manuscript ID	97675
Country	China

Received	2024-06-05 04:02
Peer-Review Started	2024-06-05 04:02
To Make the First Decision
Return for Revision	2024-09-23 09:05
Revised	2024-10-04 07:35
Second Decision	2024-11-01 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-11-01 10:47
Articles in Press	2024-11-01 10:47
Publication Fee Transferred	2024-11-01 14:54
Edit the Manuscript by Language Editor	2024-11-18 01:21
Typeset the Manuscript	2024-11-21 06:35
Publish the Manuscript Online	2024-11-26 09:16

ISSN	1949-8462 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Review
Article Title	Molecular and metabolic landscape of adenosine triphosphate-induced cell death in cardiovascular disease
Manuscript Source	Unsolicited Manuscript
All Author List	Wei Wang, Xue-Mei Wang, Hao-Long Zhang, Rui Zhao, Yong Wang, Hao-Ling Zhang and Zhi-Jing Song
ORCID	Author(s) ORCID Number Zhi-Jing Song http://orcid.org/0009-0002-3991-2907
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81960877 University Innovation Fund of Gansu Province 2021A-076 Gansu Province Science and Technology Plan 21JR7RA561 Natural Science Foundation of Gansu Province 21JR1RA267, 24JRRA1020 Education Technology Innovation Project of Gansu Province 2022A-067 Open Project of Key Laboratory of Dunhuang Medicine and Transformation of Ministry of Education DHYX21-07, DHYX22-05, DHYX21-01 Gansu Province Joint Research Fund Project 24JRRA878
Corresponding Author	Zhi-Jing Song, Clinical College of Chinese Medicine, Gansu University of Chinese Medicine, No. 35 Dingxi East Road, Chengguan District, Lanzhou 730000, Gansu Province, China. songzhijing2020@163.com
Key Words	Adenosine triphosphate induced cell death; Cardiovascular diseases; Myocardial ischemia-reperfusion injury; Molecular mechanisms; Metabolic pathways
Core Tip	Understanding the mechanisms behind adenosine triphosphate (ATP)-induced cell death (AICD) is crucial for addressing various cardiovascular diseases. AICD, triggered by elevated extracellular ATP levels, differs from other forms of cell death and has emerged as a significant contributor to conditions such as myocardial ischemia-reperfusion injury, sepsis-induced cardiomyopathy, and diabetic cardiomyopathy. This review explores the physiological roles of ATP in the cardiovascular system and delves into the molecular and metabolic mechanisms underlying AICD. Identifying therapeutic targets to mitigate AICD holds promise for treating cardiovascular diseases, although challenges remain. This review provides valuable insights and strategies for preventing and managing cardiovascular disorders.
Publish Date	2024-11-26 09:16
Citation	<p>Wang W, Wang XM, Zhang HL, Zhao R, Wang Y, Zhang HL, Song ZJ. Molecular and metabolic landscape of adenosine triphosphate-induced cell death in cardiovascular disease. <i>World J Cardiol</i> 2024; 16(12): 689-706</p>
URL	https://www.wjgnet.com/1949-8462/full/v16/i12/689.htm
DOI	https://dx.doi.org/10.4330/wjc.v16.i12.689

Full Article (PDF)	WJC-16-689-with-cover.pdf
Manuscript File	97675_Auto_Edited_030114.docx
Answering Reviewers	97675-answering-reviewers.pdf
Audio Core Tip	97675-audio.mp3
Conflict-of-Interest Disclosure Form	97675-conflict-of-interest-statement.pdf
Copyright License Agreement	97675-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	97675-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	97675-non-native-speakers.pdf
Peer-review Report	97675-peer-reviews.pdf
Scientific Misconduct Check	97675-scientific-misconduct-check.png
Scientific Editor Work List	97675-scientific-editor-work-list.pdf
CrossCheck Report	97675-crosscheck-report.pdf