Publication Name	World Journal of Gastroenterology
Manuscript ID	97702
Country	China

Received	2024-06-05 13:32
Peer-Review Started	2024-06-05 13:32
To Make the First Decision
Return for Revision	2024-08-01 19:25
Revised	2024-08-06 11:32
Second Decision	2024-08-16 04:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-08-16 09:24
Articles in Press	2024-08-16 09:24
Publication Fee Transferred	2024-08-16 11:30
Edit the Manuscript by Language Editor	2024-08-28 16:49
Typeset the Manuscript	2024-08-31 01:49
Publish the Manuscript Online	2024-09-10 09:27

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Clinical and Translational Research
Article Title	B cell-specific signatures reveal novel immunophenotyping and therapeutic targets for hepatocellular carcinoma
Manuscript Source	Unsolicited Manuscript
All Author List	Ke-Quan Xu, Zheng Gong, Jia-Ling Yang, Chu-Qi Xia, Jian-Yi Zhao and Xi Chen
ORCID	Author(s) ORCID Number Xi Chen http://orcid.org/0000-0002-6590-7565
Funding Agency and Grant Number
Corresponding Author	Xi Chen, PhD, Research Scientist, Department of Hepatobiliary and Pancreatic Surgery, Zhongnan Hospital of Wuhan University, No. 169 Donghu Road, Wuchang District, Wuhan 430071, Hubei Province, China. chenxi2022@whu.edu.cn
Key Words	B cell; Hepatocellular carcinoma; Immune microenvironment; Immunotherapy; Molecular subtype
Core Tip	We have established a reliable B cell-related genes prognostic model and novel molecular subtypes in hepatocellular carcinoma (HCC). The B cell-related genes model reveals the immune status and personalized treatment options of HCC molecular subtypes B cells may play a role in tumor cytotoxicity by activating cluster of differentiation (CD) 4 + and CD8 + T cells in HCC.
Publish Date	2024-09-10 09:27
Citation	<p>Xu KQ, Gong Z, Yang JL, Xia CQ, Zhao JY, Chen X. B cell-specific signatures reveal novel immunophenotyping and therapeutic targets for hepatocellular carcinoma. <i>World J Gastroenterol</i> 2024; 30(34): 3894-3925</p>
URL	https://www.wjgnet.com/1007-9327/full/v30/i34/3894.htm
DOI	https://dx.doi.org/10.3748/wjg.v30.i34.3894

Full Article (PDF)	WJG-30-3894-with-cover.pdf
Manuscript File	97702_Auto_Edited_003544.docx
Answering Reviewers	97702-answering-reviewers.pdf
Audio Core Tip	97702-audio.m4a
Biostatistics Review Certificate	97702-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	97702-conflict-of-interest-statement.pdf
Copyright License Agreement	97702-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	97702-non-native-speakers.pdf
Supplementary Material	97702-supplementary-material.pdf
Peer-review Report	97702-peer-reviews.pdf
Scientific Misconduct Check	97702-scientific-misconduct-check.png
Scientific Editor Work List	97702-scientific-editor-work-list.pdf
CrossCheck Report	97702-crosscheck-report.png
CrossCheck Report	97702-crosscheck-report.pdf