Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	97751
Country	China

Received	2024-06-07 01:32
Peer-Review Started	2024-06-07 01:32
To Make the First Decision
Return for Revision	2024-08-31 08:29
Revised	2024-09-06 07:26
Second Decision	2024-09-14 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-09-14 06:49
Articles in Press	2024-09-14 06:49
Publication Fee Transferred	2024-09-16 08:28
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-09-19 02:40
Publish the Manuscript Online	2024-09-28 04:34

ISSN	1948-9366 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Leukopenia-a rare complication secondary to invasive liver abscess syndrome in a patient with diabetes mellitus: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Chun-Yan Niu, Bang-Tao Yao, Hua-Yi Tao, Xin-Gui Peng, Qing-Hua Zhang, Yue Chen and Lu Liu
ORCID	Author(s) ORCID Number Chun-Yan Niu http://orcid.org/0000-0001-8226-8040 Bang-Tao Yao http://orcid.org/0000-0003-4036-7440 Yue Chen http://orcid.org/0009-0007-8339-2984
Funding Agency and Grant Number	Funding Agency Grant Number 2022 Nanjing Health Science and Technology Development Special Fund Support Project No. YKK22240
Corresponding Author	Yue Chen, MD, Chief Doctor, Department of Gastroenterology, Nanjing Lishui People’s Hospital, Zhongda Hospital Lishui Branch, Southeast University, No. 86 Chongwen Road, Lishui District, Nanjing 211200, Jiangsu Province, China. sanyudouzheng@126.com
Key Words	Invasive liver abscess syndrome; Klebsiella pneumoniae; Leukopenia; Thrombocytopenia; Treatment; Prognosis; Case report
Core Tip	Thrombocytopenia is a common complication of invasive liver abscess syndrome (ILAS). However, there have been no reports of concurrent leukopenia with ILAS so far. This patient presented with a sustained high fever, abdominal distension, and pain after hospitalization. He subsequently developed multiple organ and system dysfunction, as well as an atypical leukopenia coexisting with thrombocytopenia. These features are often used as indicators of the severity of the disease. Klebsiella pneumoniae was detected on blood cultures, and antibiotics were adjusted timely based on drug sensitivity test results. After systemic support and blood glucose management treatment, the patient’s condition resolved. Early antimicrobial therapy is an effective measure to control infection and improve prognosis.
Publish Date	2024-09-28 04:34
Citation	<p>Niu CY, Yao BT, Tao HY, Peng XG, Zhang QH, Chen Y, Liu L. Leukopenia-a rare complication secondary to invasive liver abscess syndrome in a patient with diabetes mellitus: A case report. <i>World J Gastrointest Surg</i> 2024; 16(10): 3343-3349</p>
URL	https://www.wjgnet.com/1948-9366/full/v16/i10/3343.htm
DOI	https://dx.doi.org/10.4240/wjgs.v16.i10.3343

Full Article (PDF)	WJGS-16-3343-with-cover.pdf
CARE Checklist–2016	97751-CARE-Checklist-2016.pdf
Manuscript File	97751_Auto_Edited_010816.docx
Answering Reviewers	97751-answering-reviewers.pdf
Audio Core Tip	97751-audio.mp3
Conflict-of-Interest Disclosure Form	97751-conflict-of-interest-statement.pdf
Copyright License Agreement	97751-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	97751-foundation-statement.pdf
Signed Consent for Treatment Form(s) or Document(s)	97751-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate	97751-non-native-speakers.pdf
Peer-review Report	97751-peer-reviews.pdf
Scientific Misconduct Check	97751-scientific-misconduct-check.png
Scientific Editor Work List	97751-scientific-editor-work-list.pdf
CrossCheck Report	97751-crosscheck-report.png
CrossCheck Report	97751-crosscheck-report.pdf