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9/28/2024 4:34:21 AM | Browse: 30 | Download: 197
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 97817
Country United Kingdom
Received
2024-06-09 17:57
Peer-Review Started
2024-06-09 17:57
To Make the First Decision
Return for Revision
2024-07-02 05:12
Revised
2024-07-25 18:41
Second Decision
2024-09-03 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2024-09-03 08:48
Articles in Press
2024-09-03 08:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2024-09-13 08:14
Publish the Manuscript Online
2024-09-28 04:34
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Retrospective Cohort Study
Article Title Local excision of early rectal cancer: A multi-centre experience of transanal endoscopic microsurgery from the United Kingdom
Manuscript Source Invited Manuscript
All Author List Ahmed Farid, Matthew Tutton, Prem Thambi, TS Gill and Jim Khan
ORCID
Author(s) ORCID Number
Jim Khan http://orcid.org/0000-0002-3031-4495
Funding Agency and Grant Number
Corresponding Author Jim Khan, FCPS, FRCS (Gen Surg), MSc, PhD, Professor, Surgeon, Surgical Oncologist, Department of General Surgery, Portsmouth Hospitals NHS Trust, Queen Alexandra Hospital, Southwick Hill Road, Cosham, Portsmouth PO6 3LY, Hampshire, United Kingdom. mkhan702@aol.com
Key Words Local excision; Transanal endoscopic microsurgery; Early rectal cancer; Rectum preservation; Rectum saving
Core Tip In this multi-centre study, Trans-anal endoscopic microsurgery was employed in 222 patients of early rectal cancers (T1-T2/early T3, N0), with acceptable oncologic outcomes and morbidity. The main independent factor of survival was the completeness of local excision, while completion total mesorectal excision did not offer a survival benefit. The limitations of this study were the heterogenicity of the data, its retrospective analysis, and the non-comparative design to the total mesorectal excision, which is the standard of care. However, this rectum preservation strategy can be a substitute in selected patients, especially in the evolving era of precision medicine.
Publish Date 2024-09-28 04:34
Citation <p>Farid A, Tutton M, Thambi P, Gill T, Khan J. Local excision of early rectal cancer: A multi-centre experience of transanal endoscopic microsurgery from the United Kingdom. <i>World J Gastrointest Surg</i> 2024; 16(10): 3114-3122</p>
URL https://www.wjgnet.com/1948-9366/full/v16/i10/3114.htm
DOI https://dx.doi.org/10.4240/wjgs.v16.i10.3114
Full Article (PDF) WJGS-16-3114-with-cover.pdf
STROBE Statement 97817-STROBE-statement.pdf
Manuscript File 97817_Auto_Edited_004754.docx
Answering Reviewers 97817-answering-reviewers.pdf
Audio Core Tip 97817-audio.m4a
Biostatistics Review Certificate 97817-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 97817-conflict-of-interest-statement.pdf
Copyright License Agreement 97817-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 97817-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 97817-institutional-review-board-statement.pdf
Peer-review Report 97817-peer-reviews.pdf
Scientific Misconduct Check 97817-scientific-misconduct-check.png
Scientific Editor Work List 97817-scientific-editor-work-list.pdf
CrossCheck Report 97817-crosscheck-report.png
CrossCheck Report 97817-crosscheck-report.pdf