Publication Name	World Journal of Gastroenterology
Manuscript ID	9794
Country	China

Received	2014-02-28 10:39
Peer-Review Started	2014-03-01 10:34
To Make the First Decision	2014-05-13 19:30
Return for Revision	2014-05-21 08:09
Revised	2014-06-04 00:00
Second Decision	2014-06-26 16:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-06-26 17:44
Articles in Press	2014-06-26 18:00
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-07-22 00:04
Typeset the Manuscript	2014-09-24 12:16
Publish the Manuscript Online	2014-10-16 15:53

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Retrospective Study
Article Title	Simultaneous modulated accelerated radiation therapy for esophageal cancer: A feasibility study
Manuscript Source	Unsolicited Manuscript
All Author List	Wu-Zhe Zhang, Jian-Zhou Chen, De-Rui Li, Zhi-Jian Chen, Hong Guo, Ting-Ting Zhuang, Dong-Sheng Li, Ming-Zhen Zhou and Chuang-Zhen Chen
Funding Agency and Grant Number	Funding Agency Grant Number Shantou University Medical College Clinical Research Enhancement Initiative Science and Technology Key Project of Shantou City, China 2012-165-131
Corresponding Author	Chuang-Zhen Chen, MD, Department of Radiation Oncology, Cancer Hospital of Shantou University Medical College, No. 7 Raoping Road, Shantou 515031, Guangdong Province, China. stccz@139.com
Key Words	Simultaneous modulated accelerated radiation therapy; Three-dimensional conformal radiotherapy; Intensity-modulated radiation therapy; Esophageal cancer; Feasibility
Core Tip	The feasibility of simultaneous modulated accelerated radiotherapy (SMART) in the treatment of upper or middle thoracic esophageal cancer is evaluated in this study. Computed tomography datasets of 10 patients were used to generate SMART, conventionally-fractionated three-dimensional conformal radiotherapy (3DCRT) and intensity-modulated radiotherapy (cf-IMRT) plans, respectively. The prescribed dose for the SMART plans was 66 Gy/30 F to the gross tumor and 54 Gy/30 F to subclinical diseases. The dose for both the 3DCRT and cf-IMRT was 60 Gy/30 F to a single target volume. The results demonstrate that SMART can offer the potential for a 6 Gy simultaneous escalation in the dose delivered to the primary tumor of esophageal cancer and improve normal tissue sparing compared with 3DCRT and cf-IMRT.
Publish Date	2014-10-16 15:53
Citation	Zhang WZ, Chen JZ, Li DR, Chen ZJ, Guo H, Zhuang TT, Li DS, Zhou MZ, Chen CZ. Simultaneous modulated accelerated radiation therapy for esophageal cancer: A feasibility study. World J Gastroenterol 2014; 20(38): 13973-13980
URL	http://www.wjgnet.com/1007-9327/full/v20/i38/13973.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i38.13973

Full Article (PDF)	WJG-20-13973.pdf
Full Article (Word)	WJG-20-13973.doc
Manuscript File	9794-Review.doc
Answering Reviewers	9794-Answering reviewers.pdf
Copyright License Agreement	9794-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	Ethics_Committee_20140227233246.jpg
Non-Native Speakers of English Editing Certificate	Editing_Certificate_20140227233200.pdf
Peer-review Report	9794-Peer review.pdf
Scientific Misconduct Check	9794-CrossCheck.jpg
Scientific Editor Work List	9794-Scientific editor work list.pdf