Publication Name	World Journal of Clinical Oncology
Manuscript ID	97949
Country	China

Received	2024-06-13 09:08
Peer-Review Started	2024-06-13 09:08
To Make the First Decision
Return for Revision	2024-07-30 09:08
Revised	2024-08-09 03:57
Second Decision	2024-08-23 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-08-23 07:32
Articles in Press	2024-08-23 07:32
Publication Fee Transferred	2024-09-06 13:49
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-09-13 09:20
Publish the Manuscript Online	2024-09-29 06:08

ISSN	2218-4333 (online)
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Category	Oncology
Manuscript Type	Basic Study
Article Title	Banxia xiexin decoction prevents the development of gastric cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Guo-Xiu Zu, Ke-Yun Sun, Xi-Jian Liu, Ji-Qin Tang, Hai-Liang Huang and Tao Han
ORCID	Author(s) ORCID Number Guo-Xiu Zu http://orcid.org/0000-0002-7773-0568 Xi-Jian Liu http://orcid.org/0000-0002-6324-4673 Hai-Liang Huang http://orcid.org/0000-0003-1186-4501 Tao Han http://orcid.org/0009-0007-3858-7037
Funding Agency and Grant Number	Funding Agency Grant Number Key Program of Shandong Province No. 2016CYJS08A01-6
Corresponding Author	Hai-Liang Huang, Doctor, MD, PhD, Dean, School of Rehabilitation Medicine, Shandong University of Traditional Chinese Medicine, No. 4655 Daxue Road, Jinan 250355, Shandong Province, China. 1615080865@qq.com
Key Words	Banxia xiexin decoction; Gastric cancer; Ultra-performance liquid chromatography tandem quadrupole electrostatic field orbitrap mass spectrometry; Network pharmacology; Whole transcriptomic sequencing; Phosphoinositide 3-kinase/ protein kinase B signaling pathway
Core Tip	Based on the clinical efficacy of traditional Chinese medicine banxia xiexin decoction (BXD) in the prevention and treatment of gastric cancer, this paper explored the drug composition and drug authenticity of BXD based on Ultra-performance liquid chromatography tandem quadrupole electrostatic field orbitrap mass spectrometry technology, predicted the molecular mechanism of BXD in the treatment of gastric cancer based on network pharmacology and transcriptomics sequencing, and verified its molecular mechanism by combining in vivo and in vitro experiments, which is in line with the scope of oncology at World J Clin Oncol.
Publish Date	2024-09-29 06:08
Citation	<p>Zu GX, Sun KY, Liu XJ, Tang JQ, Huang HL, Han T. Banxia xiexin decoction prevents the development of gastric cancer. <i>World J Clin Oncol</i> 2024; 15(10): 1293-1308</p>
URL	https://www.wjgnet.com/2218-4333/full/v15/i10/1293.htm
DOI	https://dx.doi.org/10.5306/wjco.v15.i10.1293

Full Article (PDF)	WJCO-15-1293-with-cover.pdf
The ARRIVE Guidelines	97949-The-ARRIVE-Guidelines.pdf
Manuscript File	97949_Auto_Edited_062510.docx
Answering Reviewers	97949-answering-reviewers.pdf
Audio Core Tip	97949-audio.mp3
Biostatistics Review Certificate	97949-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	97949-conflict-of-interest-statement.pdf
Copyright License Agreement	97949-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	97949-foundation-statement.pdf
Institutional Animal Care and Use Committee Approval Form or Document	97949-institutional-animal-care-and-use-committee-statement.pdf
Non-Native Speakers of English Editing Certificate	97949-non-native-speakers.pdf
Peer-review Report	97949-peer-reviews.pdf
Scientific Misconduct Check	97949-scientific-misconduct-check.png
Scientific Editor Work List	97949-scientific-editor-work-list.pdf
CrossCheck Report	97949-crosscheck-report.png
CrossCheck Report	97949-crosscheck-report.pdf