Publication Name	World Journal of Gastroenterology
Manuscript ID	9795
Country	Mexico

Received	2014-02-28 10:55
Peer-Review Started	2014-03-01 10:43
First Decision by Editorial Office Director
Return for Revision	2014-03-31 10:19
Revised	2014-04-30 00:00
Publication Fee Transferred
Second Decision by Editor	2014-05-26 21:21
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2014-05-26 21:40
Articles in Press	2014-05-26 22:01
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-09-07 19:45
Publish the Manuscript Online	2014-10-07 17:32

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Virology
Manuscript Type	Autobiography
Article Title	Occult hepatitis B virus infection among Mexican human immunodeficiency virus-1-infected patients
Manuscript Source	Unsolicited Manuscript
All Author List	Ma Teresa Alvarez-Muñoz, Angelica Maldonado-Rodriguez, Othon Rojas-Montes, Rocio Torres-Ibarra, Fernanda Gutierrez-Escolano, Guillermo Vazquez-Rosales, Alejandro Gomez, Onofre Muñoz, Javier Torres and Rosalia Lira
Funding Agency and Grant Number	Funding Agency Grant Number Consejo Nacional de Ciencia y Tecnologia, Mexico 2008-C01-86717 (to Alvarez-Muñoz MT and Lira R)
Corresponding Author	Rosalia Lira, PhD, Unidad de Investigacion Medica en Enfermedades Infecciosas y Parasitarias, Hospital de Pediatria, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Cuauhtemoc 330 Col. Doctores, 06720 Mexico City, Mexico. rolica36@yahoo.com
Key Words	Hepatitis B virus; Occult hepatitis B virus infection; Human immunodeficiency virus; Hepatitis B surface antigen negative; Risk factors; Molecular diagnostics
Core Tip	In this study we assessed the frequency of occult hepatitis B infection (OHBI) in a group of 49 human immunodeficiency virus (HIV-1)+/ hepatitis B surface antigen negative (HBsAg)- Mexican patients using a highly sensitive in-house core-nested PCR and real-time PCR assays for hepatitis B virus (HBV) DNA detection. In this study we showed that the frequency of OHBI is high among HIV+/HBsAg- patients and suggests the need for testing HBV DNA in bigger populations utilizing more sentitive assays. Then, we propose to utilize the core-nested PCR assay in the initial screening for OHBI. Prospective studies would be needed to assess the clinical value of this diagnostic approach.
Publish Date	2014-10-07 17:32
Citation	Alvarez-Muñoz MT, Maldonado-Rodriguez A, Rojas-Montes O, Torres-Ibarra R, Gutierrez-Escolano F, Vazquez-Rosales G, Gomez A, Muñoz O, Torres J, Lira R. Occult hepatitis B virus infection among Mexican human immunodeficiency virus-1-infected patients. World J Gastroenterol 2014; 20(37): 13530-13537
URL	http://www.wjgnet.com/1007-9327/full/v20/i37/13530.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i37.13530

Full Article (PDF)	WJG-20-13530.pdf
Full Article (Word)	WJG-20-13530.doc
Manuscript File	9795-Review.doc
Answering Reviewers	9795-Copyright Assignment.pdf
Copyright License Agreement	9795-Copyright Assignment.pdf
Non-Native Speakers of English Editing Certificate	9795-Language certificate.pdf
Peer-review Report	9795-Peer reviews.pdf
Scientific Misconduct Check	9795-CrossCheck.jpg
Scientific Editor Work List	9795-Scientific editor work list.pdf