Publication Name	World Journal of Clinical Cases
Manuscript ID	98320
Country	Taiwan

Received	2024-06-24 10:56
Peer-Review Started	2024-06-24 10:56
To Make the First Decision
Return for Revision	2024-10-25 02:52
Revised	2024-11-03 09:00
Second Decision	2024-11-21 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-11-22 12:22
Articles in Press	2024-11-22 12:22
Publication Fee Transferred	2024-11-06 02:11
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-11-29 09:38
Publish the Manuscript Online	2024-12-04 08:24

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Otorhinolaryngology
Manuscript Type	Case Report
Article Title	Herpes simplex virus 2-induced aseptic meningitis presenting with sudden deafness: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Yuan-Cheng Liu, Shih-Hsuan Hsiao and Peir-Rong Chen
ORCID	Author(s) ORCID Number Yuan-Cheng Liu http://orcid.org/0009-0005-4356-5989 Shih-Hsuan Hsiao http://orcid.org/0009-0004-8764-1253
Funding Agency and Grant Number
Corresponding Author	Shih-Hsuan Hsiao, MD, Department of Otolaryngology, Hualien Tzu Chi Hospital, and Department of Otolaryngology, Head and Neck Surgery, School of Medicine, Tzu Chi University, 707, Sec 3, Chung-Yang Road, Hualien 970, Taiwan. hsiao62ntuh@gmail.com
Key Words	Case report; Cerebrospinal fluid; Immunocompromised; Sudden sensorineural hearing loss; Type 2 herpes simplex; Aseptic meningitis
Core Tip	We report a case of herpes simplex virus type 2 (HSV-2)-induced meningitis presenting with sudden deafness. A 68-year-old man experienced sudden left-sided hearing loss for one day. Pure-tone audiograms showed left-sided sensorineural hearing loss with an average threshold of 80 dB. After one week of high-dose steroids, the patient experienced acute changes in consciousness with left hemiparesis. Laboratory data showed no significant abnormalities. Brain computed tomography and magnetic resonance imaging revealed no intracranial hemorrhage or lesions. Cerebrospinal fluid analysis and multiplex PCR confirmed HSV-2. Acyclovir was prescribed for herpes meningoencephalitis, and symptoms gradually resolved.
Publish Date	2024-12-04 08:24
Citation	<p>Liu YC, Hsiao SH, Chen PR. Herpes simplex virus 2-induced aseptic meningitis presenting with sudden deafness: A case report. <i>World J Clin Cases</i> 2025; 13(8): 98320</p>
URL	https://www.wjgnet.com/2307-8960/full/v13/i8/98320.htm
DOI	https://dx.doi.org/10.12998/wjcc.v13.i8.98320

Full Article (PDF)	WJCC-13-98320-with-cover.pdf
CARE Checklist–2016	98320-CARE-Checklist-2016.pdf
Manuscript File	98320_Auto_Edited_100219.docx
Answering Reviewers	98320-answering-reviewers.pdf
Audio Core Tip	98320-audio.mp3
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Peer-review Report	98320-peer-reviews.pdf
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Scientific Editor Work List	98320-scientific-editor-work-list.pdf
CrossCheck Report	98320-crosscheck-report.pdf