Publication Name	World Journal of Gastroenterology
Manuscript ID	9838
Country	United States

Received	2014-03-01 15:55
Peer-Review Started	2014-03-01 19:08
To Make the First Decision	2014-03-13 18:46
Return for Revision	2014-03-23 17:30
Revised	2014-04-01 03:38
Second Decision	2014-07-22 16:50
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-07-22 17:11
Articles in Press	2014-07-22 18:27
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-11-27 17:29
Publish the Manuscript Online	2014-12-18 17:08

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Computed tomography perfusion imaging as a potential imaging biomarker of colorectal cancer
Manuscript Source	Invited Manuscript
All Author List	Koichi Hayano, Takeshi Fujishiro, Dushyant V Sahani, Asami Satoh, Tomoyoshi Aoyagi, Gaku Ohira, Toru Tochigi, Hisahiro Matsubara and Kiyohiko Shuto
Funding Agency and Grant Number
Corresponding Author	Koichi Hayano, MD, PhD, Division of Abdominal Imaging and Intervention, Department of Radiology, Massachusetts General Hospital, 55 Fruit St, White 270, Boston, MA 02114, United States. khayano@partners.org
Key Words	Colorectal cancer; Angiogenesis; Computed tomography perfusion; Antiangiogenic therapy; Chemoradiation therapy
Core Tip	The importance of angiogenesis, which is an essential process of colorectal cancer (CRC), has been established. Therefore, the in vivo measure of angiogenesis such as computed tomography (CT) perfusion (CTP) technique can be a robust imaging biomarker in CRC. Especially, CTP certainly fulfils the criteria necessary for prospective validation as a clinical trial end point, because CT is a stable platform, broadly available, and non-invasive. Therefore, we believe that CTP will plays an important role in the management of CRC, providing patients more personalized and effective treatment.
Publish Date	2014-12-18 17:08
Citation	Hayano K, Fujishiro T, Sahani DV, Satoh A, Aoyagi T, Ohira G, Tochigi T, Matsubara H, Shuto K. Computed tomography perfusion imaging as a potential imaging biomarker of colorectal cancer. World J Gastroenterol 2014; 20(46): 17345-17351
URL	http://www.wjgnet.com/1007-9327/full/v20/i46/17345.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i46.17345

Full Article (PDF)	WJG-20-17345.pdf
Full Article (Word)	WJG-20-17345.doc
Manuscript File	9838-Review.doc
Answering Reviewers	9838-Answering reviewers.pdf
Copyright License Agreement	9838-Copyright assignment.pdf
Peer-review Report	9838-Peer reivew(s).pdf
Scientific Misconduct Check	9838-CrossCheck.jpg
Scientific Editor Work List	9838-Scientific editor work list.pdf