Publication Name	World Journal of Clinical Oncology
Manuscript ID	98420
Country	Greece

Received	2024-06-25 19:56
Peer-Review Started	2024-06-25 19:56
To Make the First Decision
Return for Revision	2024-07-09 21:11
Revised	2024-07-23 06:39
Second Decision	2024-10-14 00:57
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-10-15 01:54
Articles in Press	2024-10-15 01:54
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-10-17 02:21
Publish the Manuscript Online	2024-10-22 08:28

ISSN	2218-4333 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Oncology
Manuscript Type	Editorial
Article Title	Advancements and challenges in the treatment of esophageal cancer: A comprehensive review
Manuscript Source	Invited Manuscript
All Author List	Grigorios Christodoulidis, Sara Eirini Agko, Konstantinos Eleftherios Koumarelas, Marina Nektaria Kouliou and Dimitris Zacharoulis
ORCID	Author(s) ORCID Number Grigorios Christodoulidis http://orcid.org/0000-0003-3413-0666 Sara Eirini Agko http://orcid.org/0009-0001-3449-2475 Konstantinos Eleftherios Koumarelas http://orcid.org/0000-0002-5614-4770 Marina Nektaria Kouliou http://orcid.org/0000-0002-2055-2297 Dimitris Zacharoulis http://orcid.org/0000-0003-0107-3976
Funding Agency and Grant Number
Corresponding Author	Grigorios Christodoulidis, PhD, Department of General Surgery, University Hospital of Larissa, Mezourlo, Larisa 41110, Thessalía, Greece. gregsurg@yahoo.gr
Key Words	Esophageal cancer; Immunotherapy; Treatment; Targeted therapy; Future aspects
Core Tip	Esophageal cancer remains an aggressive and deadly malignancy, with significant global incidence and mortality rates. The primary histological types, esophageal squamous cell carcinoma and esophageal adenocarcinom, exhibit distinct geographic prevalence and molecular characteristics. Early detection challenges necessitate advanced systemic treatments. Recent advancements in immunotherapy, especially immune checkpoint inhibitors, combined with traditional therapies, have shown promising improvements in survival rates.
Publish Date	2024-10-22 08:28
Citation	<p>Christodoulidis G, Agko SE, Koumarelas KE, Kouliou MN, Zacharoulis D. Advancements and challenges in the treatment of esophageal cancer: A comprehensive review. <i>World J Clin Oncol</i> 2024; 15(12): 1463-1467</p>
URL	https://www.wjgnet.com/2218-4333/full/v15/i12/1463.htm
DOI	https://dx.doi.org/10.5306/wjco.v15.i12.1463

Full Article (PDF)	WJCO-15-1463-with-cover.pdf
Manuscript File	98420_Auto_Edited_054311.docx
Answering Reviewers	98420-answering-reviewers.pdf
Audio Core Tip	98420-audio.m4a
Conflict-of-Interest Disclosure Form	98420-conflict-of-interest-statement.pdf
Copyright License Agreement	98420-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	98420-non-native-speakers.pdf
Peer-review Report	98420-peer-reviews.pdf
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Scientific Editor Work List	98420-scientific-editor-work-list.pdf
CrossCheck Report	98420-crosscheck-report.png
CrossCheck Report	98420-crosscheck-report.pdf