Publication Name	World Journal of Clinical Cases
Manuscript ID	98452
Country	India

Received	2024-08-21 03:51
Peer-Review Started	2024-06-26 09:51
To Make the First Decision
Return for Revision	2024-09-16 06:05
Revised	2024-09-26 12:04
Second Decision	2024-10-16 02:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-10-16 10:28
Articles in Press	2024-10-16 10:28
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-10-22 21:28
Typeset the Manuscript	2024-11-01 08:45
Publish the Manuscript Online	2024-11-12 06:40

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Irreversible electroporation for metastatic pancreatic carcinoma with liver metastasis: What does the evidence say
Manuscript Source	Invited Manuscript
All Author List	Ranit Seal, Akash Bararia, Bitan kumar Chattopadhyay and Nilabja Sikdar
ORCID	Author(s) ORCID Number Akash Bararia http://orcid.org/0000-0002-9069-3116 Nilabja Sikdar http://orcid.org/0000-0003-4465-472X
Funding Agency and Grant Number	Funding Agency Grant Number Department of Biotechnology, Government of India No. RLS/BT/Re-entry/05/2012
Corresponding Author	Nilabja Sikdar, PhD, Human Genetics Unit, Indian Statistical Institute, 203 BT Road, Kolkata 700108, West Bengal, India. snilabja@gmail.com
Key Words	Irreversible electroporation; Locally advanced pancreatic carcinoma; Metastatic pancreatic carcinoma; Advanced pancreatic carcinoma; Chemotherapy
Core Tip	Irreversible electroporation (IRE) is a non-thermal ablation technique that has shown promise in increasing survival for locally advanced pancreatic carcinoma when combined with chemotherapy. However, its efficacy in metastatic pancreatic carcinoma with liver metastasis is not yet established, and further high-quality studies with proper controls and randomization are needed. IRE has advantages over other ablation methods, such as preserving neighboring structures and avoiding the heat-sink effect, but it requires careful patient selection and has potential complications. The procedure is typically performed under general anesthesia and has several contraindications. While IRE may offer a new frontier in treating pancreatic cancer, its role in metastatic disease requires more research to confirm its benefits.
Publish Date	2024-11-12 06:40
Citation	<p>Seal R, Bararia A, Chattopadhyay BK, Sikdar N. Irreversible electroporation for metastatic pancreatic carcinoma with liver metastasis: What does the evidence say. <i>World J Clin Cases</i> 2025; 13(3): 98452</p>
URL	https://www.wjgnet.com/2307-8960/full/v13/i3/98452.htm
DOI	https://dx.doi.org/10.12998/wjcc.v13.i3.98452

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