| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Review |
| Article Title |
A comprehensive view of suicide: a neuro-immune-endocrine approach
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
María D Ponce-Regalado, Enrique Becerril-Villanueva, José Luis Maldonado-García, Martha C Moreno-Lafont, Gabriela Martínez-Ramírez, Salomón Jacinto-Gutiérrez, Rodrigo Arreola, Karla Sánchez-Huerta, Arturo Contis-Montes de Oca, Karla María López-Martínez, Elizabeth Bautista-Rodríguez, José Miguel Chin-Chan, Lenin Pavón and Gilberto Pérez-Sánchez |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| CONAHCYT Project |
CF-2023-I-2663 |
| Instituto Nacional de Psiquiatría Project |
NC24208.0 |
|
| Corresponding Author |
Lenin Pavón, PhD, Professor, Laboratorio de Psicoinmunología, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, 101 Calz México-Xochimilco, Ciudad de México 11340, Mexico. lkuriaki@inprf.gob.mx |
| Key Words |
Suicide; Neuroimmune endocrine; Neurotransmitters; Hormones; Cytokines; Hypothalamic-pituitary adrenal axis; Early life adversity; Inflammation; Genetic predisposition; Psychiatric disorders |
| Core Tip |
The World Health Organization defines suicide as 'any act by which an individual causes injury to himself or herself, regardless of the degree of lethal intent and knowledge of the true mobile'. The etiology of suicide is multifactorial and involves complex interactions among biological, genetic, psychological, social, and environmental factors. The purpose of this manuscript is to describe the complex interactions of neuroimmunoendocrine and genetic factors associated with suicide and their relationships with environmental factors such as exposure to early life adversity, with a focus on alterations in the HPA axis and immune system. |
| Publish Date |
2025-01-14 08:49 |
| Citation |
<p>Ponce-Regalado MD, Becerril-Villanueva E, Maldonado-García JL, Moreno-Lafont MC, Martínez-Ramírez G, Jacinto-Gutiérrez S, Arreola R, Sánchez-Huerta K, Contis-Montes de Oca A, López-Martínez KM, Bautista-Rodríguez E, Chin-Chan JM, Pavón L, Pérez-Sánchez G. A comprehensive view of suicide: a neuro-immune-endocrine approach. <i>World J Psychiatry</i> 2025; 15(2): 98484</p> |
| URL |
https://www.wjgnet.com/2220-3206/full/v15/i2/98484.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v15.i2.98484 |
