Publication Name	World Journal of Nephrology
Manuscript ID	98709
Country	Italy

Received	2024-07-03 13:32
Peer-Review Started	2024-07-03 13:33
To Make the First Decision
Return for Revision	2024-09-24 11:37
Revised	2024-09-29 12:05
Second Decision	2024-10-08 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-10-08 09:09
Articles in Press	2024-10-08 09:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-10-25 06:20
Publish the Manuscript Online	2024-11-07 08:48

ISSN	2220-6124 (online)
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Category	Urology & Nephrology
Manuscript Type	Review
Article Title	What is new in the pathogenesis and treatment of IgA glomerulonephritis
Manuscript Source	Invited Manuscript
All Author List	Maurizio Salvadori and Giuseppina Rosso
ORCID	Author(s) ORCID Number Maurizio Salvadori http://orcid.org/0000-0003-1503-2681 Giuseppina Rosso http://orcid.org/0009-0005-1014-9866
Funding Agency and Grant Number
Corresponding Author	Maurizio Salvadori, MD, Professor, Department of Renal Transplantation, Careggi University Hospital, Viale Pieraccini 18, Florence 50139, Tuscany, Italy. maurizio.salvadori1@gmail.com
Key Words	IgA nephropathy; Anti IgA autoantibodies; Genetic wide association studies; Microbiota; Anti B cell-activating factor agents; Anti A proliferation-inducing ligand agents; Anti complement agents
Core Tip	Genetic wide association studies (GWAS) and studies on microbiota allowed finding new aspects in pathogenesis of IgA nephropathy. GWAS allowed finding new genes related to the different IgA nephropathy phases. Microbiota allowed finding new roles exerted by microbes in mucosa immune system and in IgA pathogenesis. Treatment of chronic kidney disease must be always associated to the immune treatment. In the latter fundamental role is exerted by steroids. Recent studies found the relevance of anti B cell-activating factor and anti A proliferation-inducing ligand agents even if the majority of these studies are still in phases II/III. Similarly in premarketing studies are the anti-complement agents.
Publish Date	2024-11-07 08:48
Citation	<p>Salvadori M, Rosso G. What is new in the pathogenesis and treatment of IgA glomerulonephritis. <i>World J Nephrol</i> 2024; 13(4): 98709</p>
URL	https://www.wjgnet.com/2220-6124/full/v13/i4/98709.htm
DOI	https://dx.doi.org/10.5527/wjn.v13.i4.98709

Full Article (PDF)	WJN-13-98709-with-cover.pdf
Manuscript File	98709_Auto_Edited_063125.docx
Answering Reviewers	98709-answering-reviewers.pdf
Audio Core Tip	98709-audio.mp3
Conflict-of-Interest Disclosure Form	98709-conflict-of-interest-statement.pdf
Copyright License Agreement	98709-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	98709-non-native-speakers.pdf
Peer-review Report	98709-peer-reviews.pdf
Scientific Misconduct Check	98709-scientific-misconduct-check.png
Scientific Editor Work List	98709-scientific-editor-work-list.pdf
CrossCheck Report	98709-crosscheck-report.pdf