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12/11/2024 10:19:40 AM | Browse: 154 | Download: 528
Publication Name World Journal of Clinical Oncology
Manuscript ID 98812
Country China
Received
2024-07-06 08:20
Peer-Review Started
2024-07-06 08:20
First Decision by Editorial Office Director
2024-10-11 10:05
Return for Revision
2024-10-11 10:05
Revised
2024-10-13 07:38
Publication Fee Transferred
2024-10-25 00:17
Second Decision by Editor
2024-10-24 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2024-10-24 11:04
Articles in Press
2024-10-24 11:04
Edit the Manuscript by Language Editor
Typeset the Manuscript
2024-10-30 16:40
Publish the Manuscript Online
2024-12-11 10:19
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Case Report
Article Title Combined BRAF G469A mutation and echinoderm microtubule associated protein like-4-anaplastic lymphoma kinase rearrangement with resistance: A case report and review of literature
Manuscript Source Unsolicited Manuscript
All Author List Xuan Guo, Yan Liu, Yu-Ting Wang, Kan Liu and Hui Ding
ORCID
Author(s) ORCID Number
Hui Ding http://orcid.org/0000-0003-2477-461X
Funding Agency and Grant Number
Funding Agency Grant Number
the Medical Education Collaborative Innovation Fund of Jiangsu University No. JDY2022015
Corresponding Author Hui Ding, PhD, Department of Pulmonary and Critical Care Medicine, Yixing People’s Hospital of Jiangsu University, No. 1588 Xincheng Road, Yixing 214200, Jiangsu Province, China. dh1350519@163.com
Key Words Non-small-cell lung cancer; Driver mutation; Rearrangement; Resistance; Case report
Core Tip We present a non-small-cell lung cancer patient with rarely co-occurring echinoderm microtubule associated protein like-4 rearrangement and BRAF G469A mutation. The patient suffered from anaplastic lymphoma kinase tyrosine kinase inhibitors resistance and adverse events. It’s a question whether the process of reducing dosage of alectinib was easier to cause resistance. Although we were unable to assess the correlation between BRAF G469A mutation and anaplastic lymphoma kinase tyrosine kinase inhibitors resistance, the safety and efficacy of combination therapy to multiple driver oncogenes are important in clinic.
Publish Date 2024-12-11 10:19
Citation

Guo X, Liu Y, Wang YT, Liu K, Ding H. Combined BRAF G469A mutation and echinoderm microtubule associated protein like-4-anaplastic lymphoma kinase rearrangement with resistance: A case report and review of literature. World J Clin Oncol 2025; 16(2): 98812

URL https://www.wjgnet.com/2218-4333/full/v16/i2/98812.htm
DOI https://dx.doi.org/10.5306/wjco.v16.i2.98812
Full Article (PDF) WJCO-16-98812-with-cover.pdf
CARE Checklist–2016 98812-CARE-Checklist-2016.pdf
Manuscript File 98812_Auto_Edited_091925.docx
Answering Reviewers 98812-answering-reviewers.pdf
Audio Core Tip 98812-audio.mp3
Conflict-of-Interest Disclosure Form 98812-conflict-of-interest-statement.pdf
Copyright License Agreement 98812-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 98812-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 98812-non-native-speakers.pdf
Peer-review Report 98812-peer-reviews.pdf
Scientific Misconduct Check 98812-scientific-misconduct-check.png
Scientific Editor Work List 98812-scientific-editor-work-list.pdf
CrossCheck Report 98812-crosscheck-report.pdf