Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	98872
Country	China

Received	2024-07-09 03:08
Peer-Review Started	2024-07-09 03:08
To Make the First Decision
Return for Revision	2024-08-24 18:55
Revised	2024-09-05 07:25
Second Decision	2024-09-19 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-09-19 08:27
Articles in Press	2024-09-19 08:27
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-09-24 13:02
Publish the Manuscript Online	2024-12-12 09:30

ISSN	1948-5204 (online)
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Category	Biochemistry & Molecular Biology
Manuscript Type	Editorial
Article Title	Characteristics of gut microbiota dysbiosis in patients with colorectal polyps
Manuscript Source	Invited Manuscript
All Author List	Xian-Rong Wu, Xiao-Hong He and Yong-Fang Xie
ORCID	Author(s) ORCID Number Yong-Fang Xie http://orcid.org/0000-0002-8210-5732
Funding Agency and Grant Number
Corresponding Author	Yong-Fang Xie, MD, Doctor, Doctor, School of Life Health Informatign Science and Engineering, Chongqing Post and Communications University, No. 2 Chongwen Road, Huangjiao Ya, Nanan District, Chongqing 400065, China. xyf1688@126.com
Key Words	Recurrent colorectal polyps; Gut microbiota dysbiosis; Klebsiella; Probiotics; Intestinal inflammation; Microbial intervention strategy
Core Tip	This review addresses gut microbiota dysbiosis in patients with recurrent colorectal polyps, noting increased levels of Klebsiella, Parvimonas, and Clostridium and decreased levels of Bifidobacterium and Lactobacillus. This dysbiosis may promote polyp formation and recurrence by creating an inflammatory gut environment. A reduction in probiotics weakens intestinal barrier function, while an increase in pathogens further degrades the gut through their metabolic products and toxins. These changes are also observed in colorectal cancer, inflammatory bowel disease, autism spectrum disorder, and metabolic syndrome. Regulating the gut microbiota, particularly by increasing the use of probiotics, may restore gut health and prevent polyp recurrence. Future research should explore specific mechanisms and evaluate long-term effects.
Publish Date	2024-12-12 09:30
Citation	<p>Wu XR, He XH, Xie YF. Characteristics of gut microbiota dysbiosis in patients with colorectal polyps. <i>World J Gastrointest Oncol</i> 2025; 17(1): 98872</p>
URL	https://www.wjgnet.com/1948-5204/full/v17/i1/98872.htm
DOI	https://dx.doi.org/10.4251/wjgo.v17.i1.98872

Full Article (PDF)	WJGO-17-98872-with-cover.pdf
Manuscript File	98872_Auto_Edited_035507.docx
Answering Reviewers	98872-answering-reviewers.pdf
Audio Core Tip	98872-audio.mp4
Conflict-of-Interest Disclosure Form	98872-conflict-of-interest-statement.pdf
Copyright License Agreement	98872-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	98872-non-native-speakers.pdf
Peer-review Report	98872-peer-reviews.pdf
Scientific Misconduct Check	98872-scientific-misconduct-check.png
Scientific Editor Work List	98872-scientific-editor-work-list.pdf
CrossCheck Report	98872-crosscheck-report.pdf