Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	98927
Country	China

Received	2024-07-09 10:12
Peer-Review Started	2024-07-09 10:12
To Make the First Decision
Return for Revision	2024-11-11 07:25
Revised	2024-11-22 10:15
Second Decision	2024-12-10 02:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-12-10 06:30
Articles in Press	2024-12-10 06:30
Publication Fee Transferred	2024-11-30 11:12
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-12-17 09:08
Publish the Manuscript Online	2025-01-18 08:12

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Meta-Analysis
Article Title	Efficacy of sorafenib combined with transarterial chemoembolization in the treatment of advanced hepatocellular carcinoma: A meta-analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Mei Xu, Si-Rui Zhou, Ya-Ling Li, Chen-Hao Zhang, Da-Zhong Liao and Xiao-Li Wang
ORCID	Author(s) ORCID Number Ya-Ling Li http://orcid.org/0000-0003-1019-397X Xiao-Li Wang http://orcid.org/0000-0003-3911-1907
Funding Agency and Grant Number	Funding Agency Grant Number Sichuan Science and Technology Program 2022YFS0625
Corresponding Author	Xiao-Li Wang, MD, Department of Oncology, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, No. 182 Chunhui Road, Luzhou 646000, Sichuan Province, China. wxl0427easy@163.com
Key Words	Sorafenib; Transarterial chemoembolization; Hepatocellular carcinoma; Overall survival; Progression-free survival; Meta-analysis
Core Tip	This meta-analysis synthesizes current research to assess the efficacy of combining sorafenib with transarterial chemoembolization (TACE), aiming to enhance survival outcomes in patients with advanced hepatocellular carcinoma (HCC). Our comprehensive review, adhering to PRISMA guidelines, included twelve studies and 1174 patients, revealing that the combination therapy significantly improves both overall survival and progression-free survival compared to sorafenib or TACE alone. These results advocate for the integration of this combined approach in clinical practice, potentially setting a new benchmark in the treatment protocols for advanced HCC.
Publish Date	2025-01-18 08:12
Citation	<p>Xu M, Zhou SR, Li YL, Zhang CH, Liao DZ, Wang XL. Efficacy of sorafenib combined with transarterial chemoembolization in the treatment of advanced hepatocellular carcinoma: A meta-analysis. <i>World J Gastrointest Oncol</i> 2025; 17(2): 98927</p>
URL	https://www.wjgnet.com/1948-5204/full/v17/i2/98927.htm
DOI	https://dx.doi.org/10.4251/wjgo.v17.i2.98927

Full Article (PDF)	WJGO-17-98927-with-cover.pdf
PRISMA 2009 Checklist	98927-PRISMA-2009-Checklist.pdf
Manuscript File	98927_Auto_Edited_083721.docx
Answering Reviewers	98927-answering-reviewers.pdf
Audio Core Tip	98927-audio.mp3
Biostatistics Review Certificate	98927-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	98927-conflict-of-interest-statement.pdf
Copyright License Agreement	98927-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	98927-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	98927-non-native-speakers.pdf
Peer-review Report	98927-peer-reviews.pdf
Scientific Misconduct Check	98927-scientific-misconduct-check.png
Scientific Editor Work List	98927-scientific-editor-work-list.pdf
CrossCheck Report	98927-crosscheck-report.pdf