Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	99068
Country	India

Received	2024-07-12 10:52
Peer-Review Started	2024-07-12 10:52
To Make the First Decision
Return for Revision	2024-10-20 10:54
Revised	2024-10-24 11:59
Second Decision	2024-12-10 02:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-12-10 03:39
Articles in Press	2024-12-10 03:39
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-12-17 12:50
Typeset the Manuscript	2025-01-22 03:34
Publish the Manuscript Online	2025-02-14 10:33

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Letter to the Editor
Article Title	Current research status and future directions of hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	Meer M Chisthi
ORCID	Author(s) ORCID Number Meer M Chisthi http://orcid.org/0000-0003-2794-0062
Funding Agency and Grant Number
Corresponding Author	Meer M Chisthi, Professor, Department of General Surgery, Government Medical College Pathanamthitta, Aanakuthi, Konni 689691, Kerala, India. meerchisthi@gmail.com
Key Words	Hepatic arterial infusion chemotherapy; Hepatocellular carcinoma; Network meta-analysis; Interventional therapy; Systemic treatment
Core Tip	Hepatic arterial infusion chemotherapy (HAIC) has been shown to offer significantly superior efficacy and safety compared to traditional treatments such as Sorafenib and transarterial chemoembolization for patients suffering from advanced hepatocellular carcinoma (HCC). By directly delivering high concentrations of chemotherapeutic agents to the liver tumor through the hepatic artery, HAIC maximizes tumoricidal effects while minimizing systemic side effects. This review underscores the promising clinical outcomes associated with HAIC. Through continued investigation and validation, HAIC has the potential to become a cornerstone in the treatment paradigm for advanced HCC, providing patients with a more effective and safer therapeutic option.
Publish Date	2025-02-14 10:33
Citation	<p>Chisthi MM. Current research status and future directions of hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma. <i>World J Gastrointest Oncol</i> 2025; 17(3): 99068</p>
URL	https://www.wjgnet.com/1948-5204/full/v17/i3/99068.htm
DOI	https://dx.doi.org/10.4251/wjgo.v17.i3.99068

Full Article (PDF)	WJGO-17-99068-with-cover.pdf
Manuscript File	99068_Auto_Edited_011615.docx
Answering Reviewers	99068-answering-reviewers.pdf
Audio Core Tip	99068-audio.mp3
Conflict-of-Interest Disclosure Form	99068-conflict-of-interest-statement.pdf
Copyright License Agreement	99068-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	99068-non-native-speakers.pdf
Peer-review Report	99068-peer-reviews.pdf
Scientific Misconduct Check	99068-scientific-misconduct-check.png
Scientific Editor Work List	99068-scientific-editor-work-list.pdf
CrossCheck Report	99068-crosscheck-report.pdf