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Articles Published Processes
10/16/2014 3:53:00 PM | Browse: 1457 | Download: 1467
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Received |
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2014-03-03 21:58 |
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Peer-Review Started |
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2014-03-04 08:45 |
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To Make the First Decision |
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2014-03-27 20:59 |
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Return for Revision |
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2014-03-31 10:21 |
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Revised |
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2014-04-29 00:00 |
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Second Decision |
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2014-05-26 21:23 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-05-26 21:42 |
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Articles in Press |
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2014-05-26 22:03 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-09-24 09:29 |
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Publish the Manuscript Online |
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2014-10-16 15:53 |
Category |
Oncology |
Manuscript Type |
Topic Highlights |
Article Title |
MicroRNAs: Promising chemoresistance biomarkers in gastric cancer with diagnostic and therapeutic potential
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Manuscript Source |
Invited Manuscript |
All Author List |
Christiane Matuszcak, Joerg Haier, Richard Hummel and Kirsten Lindner |
Funding Agency and Grant Number |
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Corresponding Author |
Dr. Kirsten Lindner, Department of General and Visceral Surgery, Muenster University Hospital, Waldeyerstr. 1, 48149 Muenster, Germany. kirsten.lindner@ukmuenster.de |
Key Words |
MicroRNAs; Biomarker; Chemoresistance; Gastric cancer; Diagnostic; Therapeutic |
Core Tip |
MicroRNAs (miRNAs) are a relatively new class of gene expression regulators, being involved in cancer initiation and progression. There is evidence that miRNAs impact on resistance towards various chemotherapeutics and are accessible and detectable in different tissue types, including blood samples, with great stability. Taken together, miRNAs seem to have great potential as new biomarkers for diagnostic and therapeutic approaches. This current review aims to provide an overview about the potential clinical applicability of miRNAs as biomarkers for chemoresistance in gastric cancer (GC), focusing on prediction and modulation of sensitivity and resistance towards chemotherapeutic drugs in GC. |
Publish Date |
2014-10-16 15:53 |
Citation |
Matuszcak C, Haier J, Hummel R, Lindner K. MicroRNAs: Promising chemoresistance biomarkers in gastric cancer with diagnostic and therapeutic potential. World J Gastroenterol 2014; 20(38): 13658-13666 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i38/13658.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i38.13658 |
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