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10/16/2014 3:53:00 PM | Browse: 1300 | Download: 1230
Publication Name World Journal of Gastroenterology
Manuscript ID 9912
Country Germany
Received
2014-03-03 21:58
Peer-Review Started
2014-03-04 08:45
To Make the First Decision
2014-03-27 20:59
Return for Revision
2014-03-31 10:21
Revised
2014-04-29 00:00
Second Decision
2014-05-26 21:23
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-05-26 21:42
Articles in Press
2014-05-26 22:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-09-24 09:29
Publish the Manuscript Online
2014-10-16 15:53
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Topic Highlights
Article Title MicroRNAs: Promising chemoresistance biomarkers in gastric cancer with diagnostic and therapeutic potential
Manuscript Source Invited Manuscript
All Author List Christiane Matuszcak, Joerg Haier, Richard Hummel and Kirsten Lindner
Funding Agency and Grant Number
Corresponding Author Dr. Kirsten Lindner, Department of General and Visceral Surgery, Muenster University Hospital, Waldeyerstr. 1, 48149 Muenster, Germany. kirsten.lindner@ukmuenster.de
Key Words MicroRNAs; Biomarker; Chemoresistance; Gastric cancer; Diagnostic; Therapeutic
Core Tip MicroRNAs (miRNAs) are a relatively new class of gene expression regulators, being involved in cancer initiation and progression. There is evidence that miRNAs impact on resistance towards various chemotherapeutics and are accessible and detectable in different tissue types, including blood samples, with great stability. Taken together, miRNAs seem to have great potential as new biomarkers for diagnostic and therapeutic approaches. This current review aims to provide an overview about the potential clinical applicability of miRNAs as biomarkers for chemoresistance in gastric cancer (GC), focusing on prediction and modulation of sensitivity and resistance towards chemotherapeutic drugs in GC.
Publish Date 2014-10-16 15:53
Citation Matuszcak C, Haier J, Hummel R, Lindner K. MicroRNAs: Promising chemoresistance biomarkers in gastric cancer with diagnostic and therapeutic potential. World J Gastroenterol 2014; 20(38): 13658-13666
URL http://www.wjgnet.com/1007-9327/full/v20/i38/13658.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i38.13658
Full Article (PDF) WJG-20-13658.pdf
Full Article (Word) WJG-20-13658.doc
Manuscript File 9912-Review.docx
Answering Reviewers 9912-Answering reviewers.pdf
Copyright License Agreement 9912-Copyright Assignment.pdf
Peer-review Report 9912-Peer reviews.pdf
Scientific Misconduct Check 9912-CrossCheck.jpg
Scientific Editor Work List 9912-Scientific editor work list.pdf