Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	99122
Country	China

Received	2024-07-15 05:44
Peer-Review Started	2024-07-14 10:16
To Make the First Decision
Return for Revision	2024-10-28 07:50
Revised	2024-11-09 12:34
Second Decision	2024-11-26 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-11-26 07:09
Articles in Press	2024-11-26 07:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-11-30 02:54
Publish the Manuscript Online	2024-12-27 13:37

ISSN	1948-9366 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Immunology
Manuscript Type	Editorial
Article Title	Early identification and multidisciplinary management of immune checkpoint inhibitors associated colitis can improve patient outcomes
Manuscript Source	Invited Manuscript
All Author List	Liang Wang, Sheng-Mei Zhang and Xiao-Qian Chen
ORCID	Author(s) ORCID Number Liang Wang http://orcid.org/0000-0002-4206-5043 Xiao-Qian Chen http://orcid.org/0000-0002-9699-5588
Funding Agency and Grant Number	Funding Agency Grant Number 2021 Key Topic of Qinghai Provincial Health System–Guiding Plan Topic No. 2021-WJZDX-43
Corresponding Author	Xiao-Qian Chen, Department of Gastrointestinal Oncology Surgery, The Affiliated Hospital of Qinghai University, The Affiliated Cancer Hospital of Qinghai University, No. 29 Tongren Road, Xining 810000, Qinghai Province, China. cxq925@163.com
Key Words	Immune checkpoint inhibitors; Immune-related adverse events; Immune checkpoint inhibitor-associated colitis; Immunotherapy; Multidisciplinary management
Core Tip	The application of various immune checkpoint inhibitors (ICIs) in treating various malignant tumors has yielded remarkable clinical efficacy, significantly improving patient prognosis. However, while ICIs strengthen anti-tumor immunity, they can also induce autoimmune damage and immune-related adverse events (irAEs), with immune checkpoint inhibitor (ICI)-associated colitis being relatively common. This condition may lead to treatment interruptions, drug discontinuation, and reduced treatment efficacy. Severe irAEs can even be life-threatening. Thus, vigilance for ICI-associated colitis is essential when patients exhibit symptoms like diarrhea and abdominal pain during or after ICI treatment. Early identification, multidisciplinary management, and continuous monitoring are critical to improving patient outcomes.
Publish Date	2024-12-27 13:37
Citation	<p>Wang L, Zhang SM, Chen XQ. Early identification and multidisciplinary management of immune checkpoint inhibitors associated colitis can improve patient outcomes. <i>World J Gastrointest Surg</i> 2025; 17(1): 99122</p>
URL	https://www.wjgnet.com/1948-9366/full/v17/i1/99122.htm
DOI	https://dx.doi.org/10.4240/wjgs.v17.i1.99122

Full Article (PDF)	WJGS-17-99122-with-cover.pdf
Manuscript File	99122_Auto_Edited_112739.docx
Answering Reviewers	99122-answering-reviewers.pdf
Audio Core Tip	99122-audio.mp3
Conflict-of-Interest Disclosure Form	99122-conflict-of-interest-statement.pdf
Copyright License Agreement	99122-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	99122-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	99122-non-native-speakers.pdf
Peer-review Report	99122-peer-reviews.pdf
Scientific Misconduct Check	99122-scientific-misconduct-check.png
Scientific Editor Work List	99122-scientific-editor-work-list.pdf
CrossCheck Report	99122-crosscheck-report.pdf