Publication Name	World Journal of Stem Cells
Manuscript ID	99132
Country	China

Received	2024-07-23 11:22
Peer-Review Started	2024-07-23 11:22
To Make the First Decision
Return for Revision	2024-11-11 08:36
Revised	2024-11-23 16:01
Second Decision	2025-01-08 02:32
Accepted by Journal Editor-in-Chief	2025-01-08 14:23
Accepted by Executive Editor-in-Chief	2025-01-16 06:58
Articles in Press	2025-01-16 06:58
Publication Fee Transferred	2024-11-25 12:07
Edit the Manuscript by Language Editor	2025-01-22 21:17
Typeset the Manuscript	2025-02-10 01:25
Publish the Manuscript Online	2025-02-24 05:39

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Cell & Tissue Engineering
Manuscript Type	Basic Study
Article Title	WDR36 inhibited the osteogenic differentiation and migration of periodontal ligament stem cells
Manuscript Source	Unsolicited Manuscript
All Author List	Yi Wang, Feng-Qiu Zhang, Zhi-Peng Fan, Xin-Ling Zhu, Wan-Hao Yan and Xiu-Li Zhang
ORCID	Author(s) ORCID Number Yi Wang http://orcid.org/0009-0005-0904-7635 Feng-Qiu Zhang http://orcid.org/0000-0001-5782-0761 Zhi-Peng Fan http://orcid.org/0000-0003-0629-3476
Funding Agency and Grant Number	Funding Agency Grant Number Beijing Natural Science Foundation 7192076
Corresponding Author	Feng-Qiu Zhang, Department of Periodontics School of Stomatology, Capital Medical University, No. 9 Fanjiacun Road, Fengtai District, Beijing 100070, China. zhfengqiu@126.com
Key Words	Periodontal ligament stem cells; Periodontal tissue regeneration; Icariin; WDR36; Osteogenic differentiation
Core Tip	Periodontal ligament stem cells (PDLSCs) are an important cell source for periodontal tissue regeneration. They can migrate to injured areas to promote tissue repair, induce osteogenic differentiation for bone tissue regeneration, and delay tissue loss by inhibiting senescence. In this study, we investigated the regulatory function of the WDR36 on PDLSCs and found that the WDR36 inhibits the migration, osteogenic differentiation, and senescence of PDLSCs. WDR36 may serve as a new candidate target for periodontal tissue regeneration.
Publish Date	2025-02-24 05:39
Citation	<p>Wang Y, Zhang FQ, Fan ZP, Zhu XL, Yan WH, Zhang XL. WDR36 inhibited the osteogenic differentiation and migration of periodontal ligament stem cells. <i>World J Stem Cells</i> 2025; 17(2): 99132</p>
URL	https://www.wjgnet.com/1948-0210/full/v17/i2/99132.htm
DOI	https://dx.doi.org/10.4252/wjsc.v17.i2.99132

Full Article (PDF)	WJSC-17-99132-with-cover.pdf
Manuscript File	99132_Auto_Edited_053204.docx
Answering Reviewers	99132-answering-reviewers.pdf
Audio Core Tip	99132-audio.mp3
Biostatistics Review Certificate	99132-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	99132-conflict-of-interest-statement.pdf
Copyright License Agreement	99132-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	99132-foundation-statement.pdf
Institutional Review Board Approval Form or Document	99132-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	99132-non-native-speakers.pdf
Supplementary Material	99132-supplementary-material.pdf
Peer-review Report	99132-peer-reviews.pdf
Journal Editor-in-Chief Review Report	99132-journal-editor-in-chief.pdf
Scientific Misconduct Check	99132-scientific-misconduct-check.png
Scientific Editor Work List	99132-scientific-editor-work-list.pdf
CrossCheck Report	99132-crosscheck-report.pdf